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ADIRF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9629372

MBS9629372 is an antibody targeting ADIRF. Also known as APM2 Antibody. Reactive in Human. Host: Rabbit. More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APM2 (ADIRF), Polyclonal Antibody
Full Product Name
APM2 Antibody
Product Gene Name
Product Synonym Names
Adipose most abundant gene transcript 2 protein; Adipose specific 2; APM 2; C10orf116; Chromosome 10 open reading frame 116; OTTHUMP00000020019; RP11-96C23.4
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Concentration
1mg/ml (lot specific)
Specificity
APM2 Antibody detects endogenous levels of total APM2.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Antibody/Peptide Pairs
ADIRF peptide (MBS9631755) is used for blocking the activity of ADIRF antibody (MBS9629372)
Molecular Weight
7855 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (88728188..88730666). Location: 10q23.2
3D Structure
ModBase 3D Structure for Q15847
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Tissue Specificity
Expressed in adipose tissue (at protein level). Highly expressed in omental and subcutaneous adipose tissues. Expressed in heart, cornea, liver, kidney and spleen.
Function
Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin.

Product Categories/Family for anti-ADIRF antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ADIRF antibody
ELISA (EIA)(peptide)
Application Notes for anti-ADIRF antibody
ELISA(peptide): 1:20000-1:40000

Other Notes

Small volumes of anti-ADIRF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADIRF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
adipogenesis regulatory factor
NCBI Official Synonym Full Names
adipogenesis regulatory factor
NCBI Official Symbol
ADIRF
NCBI Official Synonym Symbols
AFRO; APM2; apM-2; C10orf116; RP11-96C23.4
UniProt Protein Name
Adipogenesis regulatory factor
UniProt Synonym Protein Names
Adipogenesis factor rich in obesity; Adipose most abundant gene transcript 2 protein; Adipose-specific protein 2
UniProt Gene Name
ADIRF
UniProt Synonym Gene Names
AFRO; APM2; C10orf116; apM-2
UniProt Entry Name
ADIRF_HUMAN
NCBI Protein Information
adipogenesis regulatory factor; adipose specific 2; adipose-specific protein 2; adipogenesis factor rich in obesity; adipose most abundant gene transcript 2 protein

NCBI Summary for ADIRF

APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008]

UniProt Comments for ADIRF

Function: Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin. Ref.6 Ref.7

Subcellular location: Nucleus Ref.7.

Tissue specificity: Expressed in adipose tissue (at protein level). Highly expressed in omental and subcutaneous adipose tissues. Expressed in heart, cornea, liver, kidney and spleen. Ref.4 Ref.7

Induction: Up-regulated during pre-adipocyte differentiation. Up-regulated following DNA damage induced by UV irradiation. Ref.6 Ref.7
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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