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GADD45 gamma Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS837278

MBS837278 is an antibody targeting GADD45 gamma. Also known as GADD45 gamma antibody. Host: Rabbit. Affinity purified Rabbit polyclonal GADD45 gamma antibody More details

$1565 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GADD45 gamma, Polyclonal Antibody
Full Product Name
GADD45 gamma antibody
Product Synonym Names
Polyclonal GADD45 gamma; Anti-GADD45 gamma; DDIT-2; GADD gamma-45; GADD gamma 45; GADD45-gamma; DDIT2; gadd-related protein 17 kD; CR6; cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; GADD45 gamma; GRP17; GADD45gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; GADD45G
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
GADD45 gamma antibody was purified by antigen-affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
17 kDa
OMIM
604949
3D Structure
ModBase 3D Structure for O95257
Cross-Reactivity
Human
Applications Tested/Suitable for anti-GADD45 gamma antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-GADD45 gamma antibody
IF:1:100-1:500
ICC:1:100-1:500
WB: 1:500-1:3000

Immunofluorescence (IF) of anti-GADD45 gamma antibody

Immunofluorescence analysis of methanol-fixed HeLa, using GADD45 gamma antibody at 1:200 dilution.
Rabbit Anti-GADD45 gamma Polyclonal Antibody – Cat# MBS837278

Western Blot (WB) of anti-GADD45 gamma antibody

Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 12 % SDS PAGE gel and GADD45 gamma antibody at a dilution of 1:1000
Rabbit Anti-GADD45 gamma Polyclonal Antibody, Western Blot (WB) – Cat# MBS837278

Other Notes

Small volumes of anti-GADD45 gamma antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GADD45 gamma. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
growth arrest and DNA damage-inducible protein GADD45 gamma
NCBI Official Synonym Full Names
growth arrest and DNA-damage-inducible, gamma
NCBI Official Symbol
GADD45G
NCBI Official Synonym Symbols
CR6; DDIT2; GRP17; GADD45gamma
UniProt Protein Name
Growth arrest and DNA damage-inducible protein GADD45 gamma
UniProt Synonym Protein Names
Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2
UniProt Gene Name
GADD45G
UniProt Synonym Gene Names
CR6; DDIT2; DDIT-2
UniProt Entry Name
GA45G_HUMAN
NCBI Protein Information
growth arrest and DNA damage-inducible protein GADD45 gamma

NCBI Summary for GADD45 gamma

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]
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UniProt Comments for GADD45 gamma

GADD45G: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. Belongs to the GADD45 family.

Protein type: DNA repair, damage; Nuclear receptor co-regulator; Apoptosis

Chromosomal Location of Human Ortholog: 9q22.1-q22.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: activation of MAPKK activity; regulation of cell cycle; apoptosis; positive regulation of apoptosis; multicellular organismal development; activation of MAPKKK activity; response to stress; negative regulation of protein kinase activity; positive regulation of JNK cascade; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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