Goat Anti-IgD Polyclonal Antibody – Cat# MBS222146

IgD Antibody – Goat Polyclonal

Name: IgD Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS222146
Price: 720 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS222146

Goat F(ab')2 anti Human IgD recognizes the delta chain of human immunoglobulin D. Reactivity to human IgG, IgA and IgM has been minimized by cross-adsorption. This antibody may react with IgD from other species. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

IgD, Polyclonal Antibody

Full Product Name

GOAT F(ab')2 ANTI HUMAN IgD:RPE (DELTA CHAIN SPECIFIC)

Product Gene Name

anti-IgD antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Form/Format

F(ab')2 fragment of IgG conjugated to R. Phycoerythrin (RPE) - liquid

Concentration

0.25 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from the date of despatch.

Molecular Weight

47,401 Da

OMIM

147170

3D Structure

ModBase 3D Structure for P01880

Perservative Stabilisers

0.1% Sodium azide
Stabilising agent
Preparation||Purified F(ab')2 fragments prepared by gel filtration chromatography followed by pepsin digestion

Buffer Solution

Phosphate buffered saline

Target Species

Human

Applications Tested/Suitable for anti-IgD antibody

ELISA (EIA), Flow cytometry (FC/FACS)

Other Notes

Small volumes of anti-IgD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IgD purchase

MBS222146 is an antibody targeting IgD. Also known as GOAT F(ab')2 ANTI HUMAN IgD:RPE (DELTA CHAIN SPECIFIC). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for IgD. It may not necessarily be applicable to this product.

NCBI GI #

193806360

NCBI GeneID

3495

NCBI Accession #

P01880.2

UniProt Primary Accession #

P01880

UniProt Secondary Accession #

Q6P4I8; Q8WU38

UniProt Related Accession #

P01880

NCBI Official Full Name

Ig delta chain C region, partial

NCBI Official Synonym Full Names

immunoglobulin heavy constant delta

NCBI Official Symbol

IGHD

UniProt Protein Name

Ig delta chain C region

UniProt Gene Name

IGHD

UniProt Entry Name

IGHD_HUMAN

UniProt Comments for IgD

IGHD: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: plasma membrane; integral to membrane

Molecular Function: antigen binding

Biological Process: immune response

Research Articles on IgD

1. Role of surface IgM and IgD on survival/apoptosis of B-cell chronic lymphocytic leukemia cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IgD antibody

Reference Product	PubMed Publications
GHRH antibody	>58 publications with IgD and GHRH
GHRHR antibody	>43 publications with IgD and GHRHR
IGHJ6 antibody	>10 publications with IgD and IGHJ6
TRH antibody	>2 publications with IgD and TRH
IGHJ4 antibody	>2 publications with IgD and IGHJ4

Pathways associated with anti-IgD antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies	Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Signaling By The B Cell Receptor (BCR) Pathway antibodies	Signaling By The B Cell Receptor (BCR) Pathway Diagram

Organs/Tissues associated with anti-IgD antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>116 publications with IgD and Blood
Brain Antibodies	>86 publications with IgD and Brain
Bone Antibodies	>47 publications with IgD and Bone
Thyroid Antibodies	>12 publications with IgD and Thyroid
Connective Tissue Antibodies	>9 publications with IgD and Connective Tissue
Bone Marrow Antibodies	>7 publications with IgD and Bone Marrow
Liver Antibodies	>6 publications with IgD and Liver
Spleen Antibodies	>6 publications with IgD and Spleen
Vascular Antibodies	>5 publications with IgD and Vascular
Skin Antibodies	>5 publications with IgD and Skin