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NAA10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9126002
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N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for… More details

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Product Overview

Online Datasheet in PDF
Product Name
NAA10, Polyclonal Antibody
Full Product Name
NAA10 Polyclonal Antibody
Product Gene Name
anti-NAA10 antibody
Product Synonym Names
ARD1A: TE2; ARD1; NATD; ARD1A; ARD1P; DXS707; MCOPS1; NAA10; OGDNS
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight
Observed MW: 26kDa
Calculated MW: 24kDa/26kDa
OMIM
phenotype 309800
3D Structure
ModBase 3D Structure for P41227
Species Reactivity/Cross-Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion proteincontaining a sequence corresponding to amino acids 161-235 of human NAA10
Calculated Molecular Weight
26kDa

Product Categories/Family for anti-NAA10 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NAA10 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-NAA10 antibody
Recommended Dilutions

WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100

Western Blot (WB) of anti-NAA10 antibody

Western blot analysis of extracts of various cell lines, using NAA10 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.
Rabbit Anti-NAA10 Polyclonal Antibody – Cat# MBS9126002

Immunohistochemistry (IHC) of anti-NAA10 antibody

Immunohistochemistry of paraffin-embedded rat lung using NAA10 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-NAA10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9126002

Immunohistochemistry (IHC) of anti-NAA10 antibody

Immunohistochemistry of paraffin-embedded human breast cancer using NAA10 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-NAA10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9126002

Immunohistochemistry (IHC) of anti-NAA10 antibody

Immunohistochemistry of paraffin-embedded human stomach using NAA10 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-NAA10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9126002

Immunohistochemistry (IHC) of anti-NAA10 antibody

Immunohistochemistry of paraffin-embedded mouse lung using NAA10 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-NAA10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9126002

Immunofluorescence (IF) of anti-NAA10 antibody

Immunofluorescence analysis of U2OS cells using NAA10 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-NAA10 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS9126002

Other Notes

Small volumes of anti-NAA10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NAA10 purchase

MBS9126002 is an antibody targeting NAA10. Also known as NAA10 Polyclonal Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NAA10. It may not necessarily be applicable to this product.

NCBI GI #
728880
NCBI GeneID
8260
NCBI Accession #
P41227.1
UniProt Primary Accession #
P41227
UniProt Secondary Accession #
A6NM98
UniProt Related Accession #
P41227
NCBI Official Full Name
N-alpha-acetyltransferase 10
NCBI Official Synonym Full Names
N(alpha)-acetyltransferase 10, NatA catalytic subunit
NCBI Official Symbol
NAA10
NCBI Official Synonym Symbols
TE2; ARD1; NATD; ARD1A; ARD1P; DXS707; MCOPS1
UniProt Protein Name
N-alpha-acetyltransferase 10
UniProt Synonym Protein Names
N-terminal acetyltransferase complex ARD1 subunit homolog A; NatA catalytic subunit Naa10
Protein Family
N-alpha-acetyltransferase
UniProt Gene Name
NAA10
UniProt Synonym Gene Names
ARD1; ARD1A; TE2
UniProt Entry Name
NAA10_HUMAN
NCBI Protein Information
N-alpha-acetyltransferase 10; natA catalytic subunit Naa10; ARD1 homolog A, N-acetyltransferase; N-acetyltransferase ARD1, human homolog of; N-alpha-acetyltransferase 10, NatA catalytic subunit; N-terminal acetyltransferase complex ARD1 subunit homolog A

UniProt Comments for NAA10

NAA10: In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Interacts with HIF1A (via its ODD domain); the interaction increases HIF1A protein stability during normoxia, and down-regulates it when induced by hypoxia. Interacts with NAA15, NAA50 and with the ribosome. Binds to MYLK. Ubiquitous. Belongs to the acetyltransferase family. ARD1 subfamily.

Protein type: Lipid Metabolism - glycerophospholipid; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine; Acetyltransferase; Secondary Metabolites Metabolism - limonene and pinene degradation; EC 2.3.1.88

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: membrane; cytoplasm; nucleolus; intracellular; nucleus

Molecular Function: peptide alpha-N-acetyltransferase activity; protein binding; N-acetyltransferase activity; acetyltransferase activity; ribosome binding

Biological Process: N-terminal protein amino acid acetylation; N-terminal peptidyl-glutamic acid acetylation; internal protein amino acid acetylation; DNA packaging; N-terminal peptidyl-serine acetylation

Disease: Ogden Syndrome; Microphthalmia, Syndromic 1
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Research Articles on NAA10

1. The study concludes that the NAA10 mutation is the cause of Lenz microphthalmia syndrome in a family, likely through the dysregulation of the retinoic acid signalling pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NAA10 antibody

 Reference Product  PubMed Publications
 HIF1A antibody  >10 publications with NAA10 and HIF1A
 NAT1 antibody  >5 publications with NAA10 and NAT1
 NAA15 antibody  >4 publications with NAA10 and NAA15
 L1CAM antibody  >3 publications with NAA10 and L1CAM
 AVPR2 antibody  >2 publications with NAA10 and AVPR2
 RENBP antibody  >1 publications with NAA10 and RENBP

Pathways associated with anti-NAA10 antibody

 Products by Pathway  Pathway Diagram
 Hypoxic And Oxygen Homeostasis Regulation Of HIF-1-alpha Pathway antibodies  Hypoxic And Oxygen Homeostasis Regulation Of HIF-1-alpha Pathway Diagram

Diseases associated with anti-NAA10 antibody

 Disease Name  Pubmed Publications
 Prostatic Diseases Antibodies  >2 publications with NAA10 and Prostatic Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with NAA10 and Carcinoma, Hepatocellular
 Cell Transformation, Neoplastic Antibodies  >2 publications with NAA10 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >2 publications with NAA10 and Liver Diseases
 Urinary Bladder Neoplasms Antibodies  >1 publications with NAA10 and Urinary Bladder Neoplasms
 Hyperplasia Antibodies  >1 publications with NAA10 and Hyperplasia
 Inflammation Antibodies  >1 publications with NAA10 and Inflammation
 Congenital Abnormalities Antibodies  >1 publications with NAA10 and Congenital Abnormalities
 Kidney Diseases Antibodies  >1 publications with NAA10 and Kidney Diseases
 Fatty Liver Antibodies  >1 publications with NAA10 and Fatty Liver

Organs/Tissues associated with anti-NAA10 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >9 publications with NAA10 and Lung
 Blood Antibodies  >4 publications with NAA10 and Blood
 Lymph Node Antibodies  >2 publications with NAA10 and Lymph Node
 Liver Antibodies  >2 publications with NAA10 and Liver
 Thyroid Antibodies  >2 publications with NAA10 and Thyroid
 Lymph Antibodies  >2 publications with NAA10 and Lymph
 Kidney Antibodies  >2 publications with NAA10 and Kidney
 Prostate Antibodies  >2 publications with NAA10 and Prostate
 Testis Antibodies  >1 publications with NAA10 and Testis
 Mammary Gland Antibodies  >1 publications with NAA10 and Mammary Gland
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