RELB Antibody – Rabbit Polyclonal

RELB: a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes. Does not associate with DNA or RelA/NFkB-p65.

Protein type: Transcription factor

Cellular Component: nucleoplasm; cytoskeleton; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; DNA binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; I-kappaB kinase/NF-kappaB cascade; T-helper 1 type immune response; transcription, DNA-dependent; cellular response to stress; T-helper 1 cell differentiation; rhythmic process; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; antigen processing and presentation; regulation of transcription, DNA-dependent; response to cytokine stimulus; innate immune response; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; inflammatory response