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STAT3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127578
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The protein encoded by this gene is a member of the STAT protein family. In response tocytokines and growth factors, STAT family members are phosphorylated by the receptorassociated kinases, and then form homo- or heterodimers that translocate to the… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STAT3, Polyclonal Antibody
Full Product Name
STAT3 Polyclonal Antibody
Product Gene Name
anti-STAT3 antibody
Product Synonym Names
STAT3; STAT3; APRF; FLJ20882; HIES; MGC16063 ;
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Molecular Weight
Observed MW: 79KDa
Calculated MW: 83kDa / 87kDa / 88kDa
Chromosome Location
Chromosome: 17; NC_000017.10 (40465342..40540586, complement). Location: 17q21.31
OMIM
102582
3D Structure
ModBase 3D Structure for P40763
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT3 (NP_003141.2).
Cross-Reactivity
Human, Mouse, Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-STAT3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-STAT3 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-STAT3 antibody

Western blot analysis of various lysates, using STAT3 Rabbit pAb (MBS127578) at 1:2500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s
Rabbit Anti-STAT3 Polyclonal Antibody – Cat# MBS127578

Immunohistochemistry (IHC) of anti-STAT3 antibody

Immunohistochemistry of paraffin-embedded mouse brain using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127578

Immunohistochemistry (IHC) of anti-STAT3 antibody

Immunohistochemistry of paraffin-embedded mouse kidney using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol
Rabbit Anti-STAT3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127578

Immunohistochemistry (IHC) of anti-STAT3 antibody

Immunohistochemistry of paraffin-embedded rat heart using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol
Rabbit Anti-STAT3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127578

Immunohistochemistry (IHC) of anti-STAT3 antibody

Immunohistochemistry of paraffin-embedded rat kidney using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127578

Immunofluorescence (IF) of anti-STAT3 antibody

Immunofluorescence analysis of PC-12 cells using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127578

Immunofluorescence (IF) of anti-STAT3 antibody

Immunofluorescence analysis of U2OS cells using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127578

Immunofluorescence (IF) of anti-STAT3 antibody

Immunofluorescence analysis of NIH/3T3 cells using STAT3 Rabbit pAb (MBS127578) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127578

Immunofluorescence (IF) of anti-STAT3 antibody

Immunofluorescence analysis of PC-12 cells using STAT3 Rabbit pAb (MBS127578) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127578

Immunofluorescence (IF) of anti-STAT3 antibody

Immunofluorescence analysis of U2OS cells using STAT3 Rabbit pAb (MBS127578) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127578

Immunofluorescence (IF) of anti-STAT3 antibody

Immunofluorescence analysis of NIH/3T3 cells using STAT3 Rabbit pAb (MBS127578) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-STAT3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127578

Product References and Citations for anti-STAT3 antibody

1. Heim, M.H. (2001) J Recept Signal Transduct Res 19, 75120. 2. Takeda, K. et al. (1997) Proc Natl Acad Sci U S A 94, 38014. 3. CatlettFalcone, R. et al. (1999) Immunity 10, 10515. 4. Garcia, R. and Jove, R. (1998) J Biomed Sci 5, 7985. 5. Bromberg, J.F. et al. (1999) Cell 98, 295303. 6. Darnell, J.E. et al. (1994) Science 264, 141521. 7. Ihle, J.N. (1995) Nature 377, 5914. 8. Wen, Z. et al. (1995) Cell 82, 24150. 9. Yokogami, K. et al. (2000) Curr Biol 10, 4750. 10. Biethahn, S. et al. (1999) Exp Hematol 27, 88594.

Other Notes

Small volumes of anti-STAT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAT3 purchase

MBS127578 is an antibody targeting STAT3. Also known as STAT3 Polyclonal Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STAT3. It may not necessarily be applicable to this product.

NCBI GI #
21618338
NCBI GeneID
6774
NCBI Accession #
NP_003141.2
UniProt Primary Accession #
P40763
UniProt Secondary Accession #
O14916; Q9BW54; A8K7B8
UniProt Related Accession #
P40763
GenBank Nucleotide #
NM_003150.3
NCBI Official Full Name
signal transducer and activator of transcription 3 isoform 2
NCBI Official Synonym Full Names
signal transducer and activator of transcription 3 (acute-phase response factor)
NCBI Official Symbol
STAT3
NCBI Official Synonym Symbols
APRF; HIES
UniProt Protein Name
Signal transducer and activator of transcription 3
UniProt Synonym Protein Names
Acute-phase response factor
Protein Family
Signal transducer and activator of transcription
UniProt Gene Name
STAT3
UniProt Synonym Gene Names
APRF
UniProt Entry Name
STAT3_HUMAN
NCBI Protein Information
signal transducer and activator of transcription 3; DNA-binding protein APRF; acute-phase response factor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STAT3 antibody

 Reference Product  PubMed Publications
 JAK2 antibody  >1230 publications with STAT3 and JAK2
 SRC antibody  >705 publications with STAT3 and SRC
 JAK1 antibody  >537 publications with STAT3 and JAK1
 CCND1 antibody  >408 publications with STAT3 and CCND1
 EGFR antibody  >363 publications with STAT3 and EGFR
 JAK3 antibody  >201 publications with STAT3 and JAK3
 MTOR antibody  >169 publications with STAT3 and MTOR
 PIAS3 antibody  >75 publications with STAT3 and PIAS3
 LEP antibody  >12 publications with STAT3 and LEP
 EP300 antibody  >8 publications with STAT3 and EP300

Pathways associated with anti-STAT3 antibody

 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram

Diseases associated with anti-STAT3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3437 publications with STAT3 and Neoplasms
 Inflammation Antibodies  >1394 publications with STAT3 and Inflammation
 Carcinoma Antibodies  >1236 publications with STAT3 and Carcinoma
 Necrosis Antibodies  >676 publications with STAT3 and Necrosis
 Adenocarcinoma Antibodies  >548 publications with STAT3 and Adenocarcinoma
 Liver Diseases Antibodies  >524 publications with STAT3 and Liver Diseases
 Breast Neoplasms Antibodies  >399 publications with STAT3 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >389 publications with STAT3 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >320 publications with STAT3 and Liver Neoplasms
 Lung Neoplasms Antibodies  >274 publications with STAT3 and Lung Neoplasms

Organs/Tissues associated with anti-STAT3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2288 publications with STAT3 and Blood
 Liver Antibodies  >1103 publications with STAT3 and Liver
 Brain Antibodies  >900 publications with STAT3 and Brain
 Vascular Antibodies  >819 publications with STAT3 and Vascular
 Muscle Antibodies  >675 publications with STAT3 and Muscle
 Lung Antibodies  >642 publications with STAT3 and Lung
 Bone Antibodies  >628 publications with STAT3 and Bone
 Heart Antibodies  >481 publications with STAT3 and Heart
 Bone Marrow Antibodies  >415 publications with STAT3 and Bone Marrow
 Skin Antibodies  >410 publications with STAT3 and Skin
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