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anti-Ku80 antibody :: Rabbit Ku80 Polyclonal Antibody

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Catalog # MBS535968
Unit / Price
  0.1 mg  /  $340 +1 FREE 8GB USB
anti-Ku80 antibody
Product Name

Ku80, Polyclonal Antibody

Also Known As

Ku80 antibody

Product Synonym Names
Polyclonal Ku80; Anti-Ku80; Ku80; Ku 80; Ku -80; Heterodimer of Ku80 subunits
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
699
3D Structure
ModBase 3D Structure for Q9I7M8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Hamster, Human, Mouse, Rat
Purity/Purification
Ku80 antibody was purified by affinity chromatography.
Form/Format
Affinity purified IgG supplied in PBS with 0.02% NaN3.
Concentration
1.0 mg/ml (lot specific)
Biological Significance
The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
Ku80 antibody was raised in rabbit using residues 323-338 [FSKVDEEQMKYKSEGK] of the 80 kDa Ku80 protein as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-Ku80 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Ku80 antibody
Affinity purified Rabbit polyclonal Ku80 antibody
Applications Tested/Suitable for anti-Ku80 antibody
Western Blot (WB)
Application Notes for anti-Ku80 antibody
WB: 1:500-1:1,000
NCBI/Uniprot data below describe general gene information for Ku80. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
79,823 Da
NCBI Official Full Name
Ku80
NCBI Official Symbol
NCBI Official Synonym Symbols
BG:DS09217.6; CG18801; DmelCG18801; DmKu80; Ku; ku80; KU80
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NCBI Protein Information
CG18801 gene product from transcript CG18801-RA
UniProt Protein Name
ATP-dependent DNA helicase II subunit 2
UniProt Gene Name
UniProt Entry Name
Q9I7M8_DROME
UniProt Comments for Ku80
Single-stranded DNA-dependent ATP-dependent helicase.
Research Articles on Ku80
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-Ku80 antibody
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