Rabbit Anti-PLIN2 Polyclonal Antibody – Cat# MBS8101786

Anti-PLIN2 rabbit polyclonal antibody at 1:500 dilution
Lane A: HEK293 Whole Cell Lysate
Lysates/proteins at 30 ug per lane.
Secondary
Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:48 kDa
Observed band size:48 kDa

ADFP/PLIN2 (PLIN2) Antibody – Rabbit Polyclonal

Name: PLIN2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8101786
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8101786

PLIN2 (Perilipin-2) is a protein that can anchor on the membrane of lipid droplets (LDs), playing a vital role in the early formation of LDs and in the regulation of LD metabolism in many types of cells. Perilipin 2 (PLIN2) is the most abundant lipid droplet… More details

$370 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ADFP/PLIN2, Polyclonal Antibody

Full Product Name

Anti-ADFP/PLIN2 Antibody, Rabbit Polyclonal

Product Gene Name

anti-PLIN2 antibody

Product Synonym Names

PLIN2 Antibody, Rabbit PAb, Antigen Affinity Purified; perilipin 2; Anti-ADFP Antibody; Anti-ADRP Antibody

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid; 0.2um filtered solution in PBS

Purity/Purification

Protein A & Antigen Affinity

Specificity

Human PLIN2

Preparation and Storage

This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Molecular Weight

48,075 Da

OMIM

103195

3D Structure

ModBase 3D Structure for Q99541

Immunogen

A synthetic peptide corresponding to the N-terminus of the Human PLIN2

Conjugation

Unconjugated

Preparation

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human PLIN2, and purified by antigen affinity chromatography.

Applications Tested/Suitable for anti-PLIN2 antibody

Western Blot (WB)

Application Notes for anti-PLIN2 antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-PLIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLIN2 purchase

MBS8101786 is an antibody targeting PLIN2. Also known as Anti-ADFP/PLIN2 Antibody, Rabbit Polyclonal. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLIN2. It may not necessarily be applicable to this product.

NCBI GI #

34577059

NCBI GeneID

123

NCBI Accession #

NP_001113.2

UniProt Primary Accession #

Q99541

UniProt Secondary Accession #

Q9BSC3

UniProt Related Accession #

Q99541

GenBank Nucleotide #

NM_001122.3

NCBI Official Full Name

perilipin-2

NCBI Official Synonym Full Names

perilipin 2

NCBI Official Symbol

PLIN2

NCBI Official Synonym Symbols

ADFP; ADRP

UniProt Protein Name

Perilipin-2

UniProt Synonym Protein Names

Adipophilin; Adipose differentiation-related protein; ADRP

Protein Family

Perilipin

UniProt Gene Name

PLIN2

UniProt Synonym Gene Names

ADFP; ADRP

UniProt Entry Name

PLIN2_HUMAN

NCBI Protein Information

perilipin-2; adipophilin; adipose differentiation-related protein

NCBI Summary for PLIN2

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

UniProt Comments for PLIN2

perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family.

Protein type: Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 9p22.1

Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane; lipid particle; nucleus; cytosol

Biological Process: long-chain fatty acid transport; response to drug; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance

Research Articles on PLIN2

1. Fat deposition within skeletal muscle in form of Plin2-coated lipid droplets increases with age and is associated with decreased muscle strength and thickness, likely through an IGF-1- and p53-dependent mechanism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLIN2 antibody

Reference Product	PubMed Publications
PPARA antibody	>2 publications with PLIN2 and PPARA
CARM1 antibody	>1 publications with PLIN2 and CARM1
RXRA antibody	>1 publications with PLIN2 and RXRA

Pathways associated with anti-PLIN2 antibody

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
HIF-1-alpha Transcription Factor Network Pathway antibodies	HIF-1-alpha Transcription Factor Network Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPARA Activates Gene Expression Pathway antibodies	PPARA Activates Gene Expression Pathway Diagram
Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies	Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram

Diseases associated with anti-PLIN2 antibody

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>12 publications with PLIN2 and Fatty Liver
Liver Diseases Antibodies	>7 publications with PLIN2 and Liver Diseases
Inflammation Antibodies	>5 publications with PLIN2 and Inflammation
Kidney Diseases Antibodies	>4 publications with PLIN2 and Kidney Diseases
Adenocarcinoma Antibodies	>3 publications with PLIN2 and Adenocarcinoma
Atrophy Antibodies	>2 publications with PLIN2 and Atrophy
Breast Neoplasms Antibodies	>2 publications with PLIN2 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>2 publications with PLIN2 and Cardiovascular Diseases
Fibrosis Antibodies	>1 publications with PLIN2 and Fibrosis
Weight Loss Antibodies	>1 publications with PLIN2 and Weight Loss

Organs/Tissues associated with anti-PLIN2 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>21 publications with PLIN2 and Muscle
Liver Antibodies	>14 publications with PLIN2 and Liver
Blood Antibodies	>12 publications with PLIN2 and Blood
Adipose Tissue Antibodies	>12 publications with PLIN2 and Adipose Tissue
Mammary Gland Antibodies	>5 publications with PLIN2 and Mammary Gland
Bone Antibodies	>5 publications with PLIN2 and Bone
Connective Tissue Antibodies	>4 publications with PLIN2 and Connective Tissue
Kidney Antibodies	>4 publications with PLIN2 and Kidney
Heart Antibodies	>2 publications with PLIN2 and Heart
Skin Antibodies	>2 publications with PLIN2 and Skin