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AGGF1 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6001527

This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
AGGF1, Polyclonal Antibody
Full Product Name
AGGF1 (GPATC7, GPATCH7, VG5Q, Angiogenic Factor with G Patch and FHA Domains 1, Angiogenic Factor VG5Q, G Patch Domain-containing Protein 7, Vasculogenesis Gene on 5q Protein, FLJ10283, HSU84971, HUS84971)
Product Gene Name
anti-AGGF1 antibody
Product Synonym Names
Anti -AGGF1 (GPATC7, GPATCH7, VG5Q, Angiogenic Factor with G Patch and FHA Domains 1, Angiogenic Factor VG5Q, G Patch Domain-containing Protein 7, Vasculogenesis Gene on 5q Protein, FLJ10283, HSU84971, HUS84971)
Immunogen Sequence
MASEAPSPPR SPPPPTSPEP ELAQLRRKVE KLERELRSCK RQVREIEKLL HHTERLYQNA ESNNQELRTQ VEELSKILQR GRNEDNKKSD VEVQTENHAP WSISDYFYQT YYNDVSLPNK VTELSDQQDQ AIETSILNSK DHLQVENDAY PGTDRTENVK YRQVDHFASN SQEPASALAT EDTSLEGSSL AESLRAAAEA AVSQTGFSYD ENTGLYFDHS TGFYYDSENQ LYYDPSTGIY YYCDVESGRY QFHSRVDLQP YPTSSTKQSK DKKLKKKRKD PDSSATNEEK DLNSEDQKAF SVEHTSCNEE ENFANMKKKA KIGIHHKNSP PKVTVPTSGN TIESPLHENI SNSTSFKDEK IMETDSEPEE GEITDSQTED SYDEAITSEG NVTAEDSEDE DEDKIWPPCI RVIVIRSPVL QIGSLFIITA VNPATIGREK DMEHTLRIPE VGVSKFHAEI YFDHDLQSYV LVDQGSQNGT IVNGKQILQP KTKCDPYVLE HGDEVKIGET VLSFHIHPGS DTCDGCERGQ VRAHLRLDKK DESFVGPTLS KEEKELEGRK ELKKIRVKYG LQNTEYEDEK TLKNPKYKDR AGKRREQVGS EGTFQRDDAP ASVHSEITDS NKGRKLLEKM GWKKGEGLGK DGGGMKTPIQ LQLRRTHAGL GTGKPSSFED VHLLQNKNKK NWDKARERFT ENFPETKPQK DDPGTMPWVK GTLE
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human AGGF1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
80,977 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (76326210..76361059). Location: 5q13.3
OMIM
149000
3D Structure
ModBase 3D Structure for Q8N302
Immunogen
Full length human AGGF1, aa1-714 (AAH32844.1).

Product Categories/Family for anti-AGGF1 antibody

Antibodies; Abs to Disease Markers
Applications Tested/Suitable for anti-AGGF1 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-AGGF1 antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-AGGF1 antibody

AGGF1 polyclonal antibody. Western Blot analysis of AGGF1 expression in HeLa.
Mouse Anti-AGGF1 Polyclonal Antibody – Cat# MBS6001527

Western Blot (WB) of anti-AGGF1 antibody

Western Blot analysis of AGGF1 expression in transfected 293T cell line by AGGF1 polyclonal antibody. Lane 1: AGGF1 transfected lysate (78.54kD). Lane 2: Non-transfected lysate.
Mouse Anti-AGGF1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6001527

Immunofluorescence (IF) of anti-AGGF1 antibody

Immunofluorescence of purified antibody to AGGF1 on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-AGGF1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6001527

Other Notes

Small volumes of anti-AGGF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGGF1 purchase

MBS6001527 is an antibody targeting AGGF1. Also known as AGGF1 (GPATC7, GPATCH7, VG5Q, Angiogenic Factor with G Patch and FHA Domains 1, Angiogenic Factor VG5Q, G Patch Domain-containing Protein 7, Vasculogenesis Gene on 5q Protein, FLJ10283, HSU84971, HUS84971). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for AGGF1. It may not necessarily be applicable to this product.

NCBI GI #
39725952
NCBI GeneID
55109
NCBI Accession #
NP_060516.2
UniProt Primary Accession #
Q8N302
UniProt Secondary Accession #
O00581; Q53YS3; Q9BU84; Q9NW66
UniProt Related Accession #
Q8N302
GenBank Nucleotide #
NM_018046.4
NCBI Official Full Name
angiogenic factor with G patch and FHA domains 1
NCBI Official Synonym Full Names
angiogenic factor with G patch and FHA domains 1
NCBI Official Symbol
AGGF1
NCBI Official Synonym Symbols
VG5Q; GPATC7; GPATCH7; HSU84971; HUS84971
UniProt Protein Name
Angiogenic factor with G patch and FHA domains 1
UniProt Synonym Protein Names
Angiogenic factor VG5Q; hVG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q protein
Protein Family
Angiogenic factor with G patch and FHA domains
UniProt Gene Name
AGGF1
UniProt Synonym Gene Names
GPATC7; GPATCH7; VG5Q; hVG5Q
UniProt Entry Name
AGGF1_HUMAN
NCBI Protein Information
angiogenic factor with G patch and FHA domains 1; angiogenic factor VG5Q; vasculogenesis gene on 5q protein; G patch domain-containing protein 7

UniProt Comments for AGGF1

AGGF1: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS). KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA processing; Cell adhesion

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: perinuclear region of cytoplasm; cytoplasm; extracellular region

Molecular Function: protein binding; nucleic acid binding

Biological Process: RNA processing; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; angiogenesis; vasculogenesis; cell adhesion

Disease: Klippel-trenaunay-weber Syndrome
Show more

Research Articles on AGGF1

1. analysis of sphingolipid modulation of angiogenic factor expression in neuroblastoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AGGF1 antibody

 Reference Product  PubMed Publications
 TNFSF12 antibody  >2 publications with AGGF1 and TNFSF12

Diseases associated with anti-AGGF1 antibody

 Disease Name  Pubmed Publications
 Klippel-Trenaunay-Weber Syndrome Antibodies  >11 publications with AGGF1 and Klippel-Trenaunay-Weber Syndrome
 Neoplasms Antibodies  >5 publications with AGGF1 and Neoplasms
 Necrosis Antibodies  >4 publications with AGGF1 and Necrosis
 Inflammation Antibodies  >2 publications with AGGF1 and Inflammation
 Hypertrophy Antibodies  >2 publications with AGGF1 and Hypertrophy
 Adenoma Antibodies  >1 publications with AGGF1 and Adenoma
 Lung Neoplasms Antibodies  >1 publications with AGGF1 and Lung Neoplasms
 Lymphoma Antibodies  >1 publications with AGGF1 and Lymphoma
 Arteriosclerosis Antibodies  >1 publications with AGGF1 and Arteriosclerosis
 Skin Neoplasms Antibodies  >1 publications with AGGF1 and Skin Neoplasms

Organs/Tissues associated with anti-AGGF1 antibody

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >11 publications with AGGF1 and Vascular
 Blood Antibodies  >4 publications with AGGF1 and Blood
 Lung Antibodies  >2 publications with AGGF1 and Lung
 Heart Antibodies  >1 publications with AGGF1 and Heart
 Muscle Antibodies  >1 publications with AGGF1 and Muscle
 Skin Antibodies  >1 publications with AGGF1 and Skin
 Uterus Antibodies  >1 publications with AGGF1 and Uterus
 Bone Antibodies  >1 publications with AGGF1 and Bone
 Embryonic Tissue Antibodies  >1 publications with AGGF1 and Embryonic Tissue
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