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ALDH1B1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9403451

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.Hsu L.C., J. Biol. Chem. 266:12257-12265(1991).Kalnine N.,… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ALDH1B1, Polyclonal Antibody
Full Product Name
ALDH1B1 Antibody
Product Gene Name
anti-ALDH1B1 antibody
Product Synonym Names
acetaldehyde dehydrogenase 5; AL1B1; aldehyde dehydrogenase X; mitochondrial; ALDH class 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1.0 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total ALDH1B1 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
57,206 Da
OMIM
100670
3D Structure
ModBase 3D Structure for P30837
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human ALDH1B1.
Target Name
ALDH1B1

Product Categories/Family for anti-ALDH1B1 antibody

Total protein Ab
Applications Tested/Suitable for anti-ALDH1B1 antibody
Western Blot (WB)
Application Notes for anti-ALDH1B1 antibody
Western blotting: 1:500~1:3000

Western Blot (WB) of anti-ALDH1B1 antibody

Western blot analysis of extracts from HepG2 cells and COS cells, using ALDH1B1 antibody.
Rabbit Anti-ALDH1B1 Polyclonal Antibody – Cat# MBS9403451

Other Notes

Small volumes of anti-ALDH1B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH1B1 purchase

MBS9403451 is an antibody targeting ALDH1B1. Also known as ALDH1B1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1B1. It may not necessarily be applicable to this product.

NCBI GI #
25777730
NCBI GeneID
219
NCBI Accession #
NP_000683.3
UniProt Primary Accession #
P30837
UniProt Secondary Accession #
Q8WX76; Q9BV45; B2R8F0
UniProt Related Accession #
P30837
GenBank Nucleotide #
NM_000692.4
NCBI Official Full Name
aldehyde dehydrogenase X, mitochondrial
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member B1
NCBI Official Symbol
ALDH1B1
NCBI Official Synonym Symbols
ALDH5; ALDHX
UniProt Protein Name
Aldehyde dehydrogenase X, mitochondrial
UniProt Synonym Protein Names
Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1
Protein Family
Aldehyde dehydrogenase
UniProt Gene Name
ALDH1B1
UniProt Synonym Gene Names
ALDH5; ALDHX
UniProt Entry Name
AL1B1_HUMAN
NCBI Protein Information
aldehyde dehydrogenase X, mitochondrial

NCBI Summary for ALDH1B1

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]
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UniProt Comments for ALDH1B1

ALDH1B1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. Belongs to the aldehyde dehydrogenase family.

Protein type: Oxidoreductase; Carbohydrate Metabolism - ascorbate and aldarate; Other Amino Acids Metabolism - beta-alanine; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - butanoate; Lipid Metabolism - glycerolipid; Mitochondrial; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.3; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - valine, leucine and isoleucine degradation

Chromosomal Location of Human Ortholog: 9p11.1

Cellular Component: nucleoplasm; mitochondrion; intracellular membrane-bound organelle; mitochondrial matrix

Molecular Function: aldehyde dehydrogenase (NAD) activity

Biological Process: ethanol catabolic process; carbohydrate metabolic process
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Research Articles on ALDH1B1

1. ALDH1 is indicative of stemness and is a biomarker marker in colon cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH1B1 antibody

 Reference Product  PubMed Publications
 ADH1B antibody  >4 publications with ALDH1B1 and ADH1B

Pathways associated with anti-ALDH1B1 antibody

 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Biosynthesis Of Antibiotics Pathway antibodies  Biosynthesis Of Antibiotics Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram

Diseases associated with anti-ALDH1B1 antibody

 Disease Name  Pubmed Publications
 Colonic Neoplasms Antibodies  >3 publications with ALDH1B1 and Colonic Neoplasms
 Lung Neoplasms Antibodies  >2 publications with ALDH1B1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >2 publications with ALDH1B1 and Breast Neoplasms
 Asthma Antibodies  >1 publications with ALDH1B1 and Asthma
 Hemorrhage Antibodies  >1 publications with ALDH1B1 and Hemorrhage
 Death Antibodies  >1 publications with ALDH1B1 and Death
 Congenital Abnormalities Antibodies  >1 publications with ALDH1B1 and Congenital Abnormalities
 Liver Diseases Antibodies  >1 publications with ALDH1B1 and Liver Diseases
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with ALDH1B1 and Drug-Related Side Effects and Adverse Reactions
 Liver Neoplasms Antibodies  >1 publications with ALDH1B1 and Liver Neoplasms

Organs/Tissues associated with anti-ALDH1B1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with ALDH1B1 and Lung
 Blood Antibodies  >4 publications with ALDH1B1 and Blood
 Liver Antibodies  >4 publications with ALDH1B1 and Liver
 Eye Antibodies  >3 publications with ALDH1B1 and Eye
 Brain Antibodies  >3 publications with ALDH1B1 and Brain
 Lymph Node Antibodies  >2 publications with ALDH1B1 and Lymph Node
 Lymph Antibodies  >2 publications with ALDH1B1 and Lymph
 Pancreas Antibodies  >2 publications with ALDH1B1 and Pancreas
 Adipose Tissue Antibodies  >1 publications with ALDH1B1 and Adipose Tissue
 Heart Antibodies  >1 publications with ALDH1B1 and Heart
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