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APOC1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS647205

APOC1 is a member of the apolipoprotein C1 family. This protein is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. More details

$785 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APOC1, Polyclonal Antibody
Full Product Name
APOC1, CT (Apolipoprotein C-I, Apo-CIB, ApoC-IB, Apolipoprotein C1, APOC1B)
Product Gene Name
Product Synonym Names
Anti -APOC1, CT (Apolipoprotein C-I, Apo-CIB, ApoC-IB, Apolipoprotein C1, APOC1B)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human APOC1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
9,332 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (45417577..45422606). Location: 19q13.2
OMIM
107710
3D Structure
ModBase 3D Structure for P02654
Immunogen
Synthetic peptide corresponding to C-ETFQKVKEKLKIDS from the C-terminal of human APOC1.

Product Categories/Family for anti-APOC1 antibody

Applications Tested/Suitable for anti-APOC1 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-APOC1 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:8000
Immunohistochemistry (Formalin-fixed, paraffin-embedded): 3.75ug/ml

Immunohistochemistry (IHC) of anti-APOC1 antibody

Human Liver (formalin-fixed, paraffin-embedded) stained with APOC1 antibody at 3.75ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.
Goat Anti-APOC1 Polyclonal Antibody – Cat# MBS647205

Other Notes

Small volumes of anti-APOC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOC1 purchase

MBS647205 is an antibody targeting APOC1. Also known as APOC1, CT (Apolipoprotein C-I, Apo-CIB, ApoC-IB, Apolipoprotein C1, APOC1B). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for APOC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
apolipoprotein C-I
NCBI Official Synonym Full Names
apolipoprotein C-I
NCBI Official Symbol
APOC1
UniProt Protein Name
Apolipoprotein C-I
UniProt Synonym Protein Names
Apolipoprotein C1
Protein Family
UniProt Gene Name
APOC1
UniProt Entry Name
APOC1_HUMAN
NCBI Protein Information
apolipoprotein C-I; apo-CIB; apoC-IB; apolipoprotein C1

NCBI Summary for APOC1

The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for APOC1

Function: Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Ref.13

Subcellular location: Secreted.

Tissue specificity: Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.

Miscellaneous: Apolipoprotein C-I is present in acidic (APOC1A) and basic (APOC1B) forms in P.paniscus, P.abelii and P.troglodytes and perhaps also in baboons and macaques. In human, the acidic form has become a pseudogene. Apo-CI makes up about 10% of the protein of the VLDL (very low density lipoprotein) and 2% of that of HDL (high density lipoprotein).

Sequence similarities: Belongs to the apolipoprotein C1 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-APOC1 antibody

 Products by Pathway  Pathway Diagram
 Statin Pathway antibodies  Statin Pathway Diagram
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