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ASH1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7051165

Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me). More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASH1L, Polyclonal Antibody
Full Product Name
ASH1L Antibody, HRP conjugated
Product Gene Name
anti-ASH1L antibody
Product Synonym Names
Histone-lysine N-methyltransferase ASH1L; ASH1-like protein; huASH1; Absent small and homeotic disks protein 1 homolog; Lysine N-methyltransferase 2H; ASH1L; KIAA1420; KMT2H
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: ASH1L (MBS7051164)
HRP Conjugated Antibody: ASH1L (MBS7051165)
Molecular Weight
332,211 Da
OMIM
AF257305 mRNA
3D Structure
ModBase 3D Structure for Q9NR48
Immunogen
Recombinant Human Histone-lysine N-methyltransferase ASH1L protein (1906-2160AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
HRP
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104088 / sc-104089 / sc-98301
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ASH1L antibody
ELISA (EIA)

Other Notes

Small volumes of anti-ASH1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASH1L purchase

MBS7051165 is an antibody targeting ASH1L. Also known as ASH1L Antibody, HRP conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASH1L. It may not necessarily be applicable to this product.

NCBI GI #
110349788
NCBI GeneID
55870
NCBI Accession #
NP_060959.2
UniProt Primary Accession #
Q9NR48
UniProt Secondary Accession #
Q59GP1; Q5T714; Q5T715; Q9P2C7
UniProt Related Accession #
Q9NR48
GenBank Nucleotide #
NM_018489.2
NCBI Official Full Name
histone-lysine N-methyltransferase ASH1L
NCBI Official Synonym Full Names
ASH1 like histone lysine methyltransferase
NCBI Official Symbol
ASH1L
NCBI Official Synonym Symbols
ASH1; KMT2H; ASH1L1
UniProt Protein Name
Histone-lysine N-methyltransferase ASH1L
UniProt Synonym Protein Names
ASH1-like protein; huASH1; Absent small and homeotic disks protein 1 homolog; Lysine N-methyltransferase 2H
Protein Family
Histone-lysine N-methyltransferase
UniProt Gene Name
ASH1L
UniProt Synonym Gene Names
KIAA1420; KMT2H; huASH1
UniProt Entry Name
ASH1L_HUMAN
NCBI Protein Information
histone-lysine N-methyltransferase ASH1L

NCBI Summary for ASH1L

This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. [provided by RefSeq, Jul 2008]

UniProt Comments for ASH1L

ASH1L: a protein methyltransferase that specifically methylates K36 of histone H3 (H3K36me). A member of the trithorax group (trxG) of transcriptional activators that is required for proper expression of Hox genes and is preferentially expressed in haematopoietic stem cells. Widely expressed, with high levels in brain, heart and kidney. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.

Protein type: Amino Acid Metabolism - lysine degradation; Cell adhesion; EC 2.1.1.43; Methyltransferase; Methyltransferase, protein lysine

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm; nucleus

Molecular Function: histone lysine N-methyltransferase activity (H3-K36 specific)

Biological Process: cell-cell signaling; DNA packaging; transcription from RNA polymerase II promoter
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Research Articles on ASH1L

1. Structural features were identified in ASH1L related to its' function and enzymatic activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ASH1L antibody

 Reference Product  PubMed Publications
 PLOD3 antibody  >1 publications with ASH1L and PLOD3

Pathways associated with anti-ASH1L antibody

 Products by Pathway  Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 Histone Modifications Pathway antibodies  Histone Modifications Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 PKMTs Methylate Histone Lysines Pathway antibodies  PKMTs Methylate Histone Lysines Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram

Diseases associated with anti-ASH1L antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >7 publications with ASH1L and Adenocarcinoma
 Lung Diseases Antibodies  >5 publications with ASH1L and Lung Diseases
 Liver Diseases Antibodies  >5 publications with ASH1L and Liver Diseases
 Neoplasms, Experimental Antibodies  >3 publications with ASH1L and Neoplasms, Experimental
 Brain Diseases Antibodies  >3 publications with ASH1L and Brain Diseases
 Inflammation Antibodies  >2 publications with ASH1L and Inflammation
 Death Antibodies  >2 publications with ASH1L and Death
 Necrosis Antibodies  >2 publications with ASH1L and Necrosis
 Liver Neoplasms Antibodies  >2 publications with ASH1L and Liver Neoplasms
 Infertility, Female Antibodies  >1 publications with ASH1L and Infertility, Female

Organs/Tissues associated with anti-ASH1L antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with ASH1L and Liver
 Lung Antibodies  >5 publications with ASH1L and Lung
 Blood Antibodies  >4 publications with ASH1L and Blood
 Brain Antibodies  >4 publications with ASH1L and Brain
 Bone Antibodies  >3 publications with ASH1L and Bone
 Muscle Antibodies  >2 publications with ASH1L and Muscle
 Embryonic Tissue Antibodies  >2 publications with ASH1L and Embryonic Tissue
 Eye Antibodies  >2 publications with ASH1L and Eye
 Thyroid Antibodies  >1 publications with ASH1L and Thyroid
 Stomach Antibodies  >1 publications with ASH1L and Stomach
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