Rabbit Anti-CCRK Polyclonal Antibody – Cat# MBS6468574

Western blot analysis of anti-CCRK Pab in mouse kidney tissue lysate (35ug/lane). CCRK(arrow) was detected using the purified Pab.

CCRK Antibody – Rabbit Polyclonal

Name: CCRK Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6468574
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6468574

MBS6468574 is an antibody targeting CCRK. Also known as CCRK, NT (Cell Division Protein Kinase 20, Cell Cycle-related Kinase, Cyclin-kinase-activating Kinase p42, CDK-activating Kinase p42, CAK-kinase p42, Cyclin-dependent Protein Kinase H, CDK20, CDCH)… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CCRK, Polyclonal Antibody

Full Product Name

CCRK, NT (Cell Division Protein Kinase 20, Cell Cycle-related Kinase, Cyclin-kinase-activating Kinase p42, CDK-activating Kinase p42, CAK-kinase p42, Cyclin-dependent Protein Kinase H, CDK20, CDCH) (MaxLight 650)

Product Gene Name

anti-CCRK antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

Purity/Purification

Purified by Ammonium Sulfate Precipitation.

Specificity

Recognizes human CCRK.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

37kDa

OMIM

610076

3D Structure

ModBase 3D Structure for Q8IZL9

Immunogen

Synthetic peptide selected from the N-terminal region of human CCRK (KLH).

Conjugate

MaxLight650

Note

Preservative Free

Product Categories/Family for anti-CCRK antibody

Antibodies; Cell Division Cycle (CDC)

Applications Tested/Suitable for anti-CCRK antibody

Western Blot (WB), FLISA

Application Notes for anti-CCRK antibody

WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-CCRK antibody

1. Fujii, H., et al., Biochem. Biophys. Res. Commun. 322(3):1052-1058 (2004). 2. Liu, Y., et al., J. Biol. Chem. 279(6):4507-4514 (2004).

Other Notes

Small volumes of anti-CCRK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CCRK. It may not necessarily be applicable to this product.

NCBI GI #

30795255

NCBI GeneID

23552

NCBI Accession #

NP_848519

UniProt Primary Accession #

Q8IZL9

UniProt Related Accession #

Q8IZL9

GenBank Nucleotide #

NM_178432

NCBI Official Full Name

cyclin-dependent kinase 20 isoform 1

NCBI Official Synonym Full Names

cyclin dependent kinase 20

NCBI Official Symbol

CDK20

NCBI Official Synonym Symbols

P42; CCRK; CDCH; PNQALRE

UniProt Protein Name

Cyclin-dependent kinase 20

UniProt Synonym Protein Names

CDK-activating kinase p42; CAK-kinase p42; Cell cycle-related kinase; Cell division protein kinase 20; Cyclin-dependent protein kinase H; Cyclin-kinase-activating kinase p42

UniProt Gene Name

CDK20

UniProt Synonym Gene Names

CCRK; CDCH; CAK-kinase p42

UniProt Entry Name

CDK20_HUMAN

NCBI Protein Information

cyclin-dependent kinase 20

NCBI Summary for CCRK

The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]

UniProt Comments for CCRK

CDK20: cyclin-dependent protein kinase H. A CMGC kinase of the CDK family. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Protein type: Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; Motility/polarity/chemotaxis; EC 2.7.11.22; CMGC group; CDK family; CCRK subfamily; CDK/CCRK subfamily

Chromosomal Location of Human Ortholog: 9q22.1

Cellular Component: cytoplasm; nucleus; cilium

Molecular Function: protein binding; cyclin-dependent protein kinase activity; ATP binding

Biological Process: regulation of cell cycle; cell division; multicellular organismal development; cell cycle; protein amino acid phosphorylation

Research Articles on CCRK

1. Results delineate an immunosuppressive mechanism of the hepatoma-intrinsic CCRK signalling and highlight an overexpressed kinase target whose inhibition might empower hepatocellular carcinoma immunotherapy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.