• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CLEC10A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6286568

CLEC10A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLEC10A, Polyclonal Antibody
Full Product Name
CLEC10A, NT (CLEC10A, CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectin superfamily member 14, Macrophage lectin 2, CD301) (PE)
Product Gene Name
anti-CLEC10A antibody
Product Synonym Names
CLEC10A; CLECSF13; CLECSF14; HML; C-type lectin domain family 10 member A; C-type lectin superfamily member 14; Macrophage lectin 2; CD301
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
28,877 Da
OMIM
605999
3D Structure
ModBase 3D Structure for Q8IUN9
Immunogen
CLEC10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CLEC10A.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-CLEC10A antibody

Antibodies; CD Markers
Applications Tested/Suitable for anti-CLEC10A antibody
Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
Application Notes for anti-CLEC10A antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-CLEC10A antibody

CLEC10A Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CLEC10A antibody detected the CLEC10A protein (arrow).
Rabbit Anti-CLEC10A Polyclonal Antibody – Cat# MBS6286568

Flow Cytometry (FC/FACS) of anti-CLEC10A antibody

CLEC10A Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-CLEC10A Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6286568

Product References and Citations for anti-CLEC10A antibody

Davila, S., et al. Genes Immun. 11(3):232-238(2010). Iijima, M., et al. Neurology 73(17):1348-1352(2009). van Vliet, S.J., et al. PLoS Pathog. 5 (10), E1000625 (2009): Suzuki, N., et al. J. Immunol. 156(1):128-135(1996).

Other Notes

Small volumes of anti-CLEC10A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLEC10A purchase

MBS6286568 is an antibody targeting CLEC10A. Also known as CLEC10A, NT (CLEC10A, CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectin superfamily member 14, Macrophage lectin 2, CD301) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLEC10A. It may not necessarily be applicable to this product.

NCBI GI #
33667103
NCBI GeneID
10462
NCBI Accession #
NP_878910.1
NCBI Related Accession #
NP_006335.2
UniProt Primary Accession #
Q8IUN9
UniProt Secondary Accession #
Q14538; Q6PIW3; A8K8J8
UniProt Related Accession #
Q8IUN9
GenBank Nucleotide #
NM_182906.2
NCBI Official Full Name
C-type lectin domain family 10 member A isoform 1
NCBI Official Synonym Full Names
C-type lectin domain family 10 member A
NCBI Official Symbol
CLEC10A
NCBI Official Synonym Symbols
HML; MGL; HML2; CD301; CLECSF13; CLECSF14
UniProt Protein Name
C-type lectin domain family 10 member A
UniProt Synonym Protein Names
C-type lectin superfamily member 14; Macrophage lectin 2; CD_antigen: CD301
Protein Family
C-type lectin domain family
UniProt Gene Name
CLEC10A
UniProt Synonym Gene Names
CLECSF13; CLECSF14; HML
UniProt Entry Name
CLC10_HUMAN
NCBI Protein Information
C-type lectin domain family 10 member A

NCBI Summary for CLEC10A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for CLEC10A

CLEC10A: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: carbohydrate binding

Biological Process: innate immune response; endocytosis
Show more

Research Articles on CLEC10A

1. These results indicate a role of MGL as an immunomodulator within the tumour microenvironment interfering with Treg functions, suggesting its possible use in the design of anticancer vaccines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CLEC10A antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with CLEC10A and Inflammation
 Lung Diseases Antibodies  >3 publications with CLEC10A and Lung Diseases
 Pneumonia Antibodies  >2 publications with CLEC10A and Pneumonia
 Nervous System Diseases Antibodies  >2 publications with CLEC10A and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with CLEC10A and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with CLEC10A and Fibrosis
 Atrophy Antibodies  >1 publications with CLEC10A and Atrophy

Organs/Tissues associated with anti-CLEC10A antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with CLEC10A and Blood
 Lung Antibodies  >3 publications with CLEC10A and Lung
 Mammary Gland Antibodies  >1 publications with CLEC10A and Mammary Gland
 Adipose Tissue Antibodies  >1 publications with CLEC10A and Adipose Tissue
 Connective Tissue Antibodies  >1 publications with CLEC10A and Connective Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000