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DDIT4L Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6004811

DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DDIT4L, Polyclonal Antibody
Full Product Name
DDIT4L (REDD2, RTP801L, DNA Damage-inducible Transcript 4-like Protein, HIF-1 Responsive Protein RTP801-like, Protein Regulated in Development and DNA Damage Response 2)
Product Gene Name
Product Synonym Names
Anti -DDIT4L (REDD2, RTP801L, DNA Damage-inducible Transcript 4-like Protein, HIF-1 Responsive Protein RTP801-like, Protein Regulated in Development and DNA Damage Response 2)
Immunogen Sequence
MVATGSLSSK NPASISELLD CGYHPESLLS DFDYWDYVVP EPNLNEVIFE ESTCQNLVKM LENCLSKSKQ TKLGCSKVLV PEKLTQRIAQ DVLRLSSTEP CGLRGCVMHV NLEIENVCKK LDRIVCDSSV VPTFELTLVF KQENCSWTSF RDFFFSRGRF SSGFRRTLIL SSGFRLVKKK LYSLIGTTVI EGS
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human DDIT4L.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
21,740 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (101106267..101111939, complement). Location: 4q24
OMIM
607730
3D Structure
ModBase 3D Structure for Q96D03
Immunogen
Full length human DDIT4L, aa1-193 (NP_660287.1).
Applications Tested/Suitable for anti-DDIT4L antibody
Western Blot (WB)
Application Notes for anti-DDIT4L antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-DDIT4L antibody

Western Blot analysis of DDIT4L expression in transfected 293T cell line by DDIT4L polyclonal antibody. Lane 1: DDIT4L transfected lysate (21.23kD). Lane 2: Non-transfected lysate.
Mouse Anti-DDIT4L Polyclonal Antibody – Cat# MBS6004811

Other Notes

Small volumes of anti-DDIT4L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DDIT4L purchase

MBS6004811 is an antibody targeting DDIT4L. Also known as DDIT4L (REDD2, RTP801L, DNA Damage-inducible Transcript 4-like Protein, HIF-1 Responsive Protein RTP801-like, Protein Regulated in Development and DNA Damage Response 2). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DDIT4L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA damage-inducible transcript 4-like protein
NCBI Official Synonym Full Names
DNA-damage-inducible transcript 4-like
NCBI Official Symbol
DDIT4L
NCBI Official Synonym Symbols
REDD2; Rtp801L
UniProt Protein Name
DNA damage-inducible transcript 4-like protein
UniProt Synonym Protein Names
HIF-1 responsive protein RTP801-like; Protein regulated in development and DNA damage response 2
UniProt Gene Name
DDIT4L
UniProt Synonym Gene Names
REDD2; RTP801L; REDD-2
UniProt Entry Name
DDT4L_HUMAN
NCBI Protein Information
DNA damage-inducible transcript 4-like protein; REDD-2; homolog of mouse SMHS1; HIF-1 responsive protein RTP801-like; regulated in development and DNA damage response 2; protein regulated in development and DNA damage response 2

UniProt Comments for DDIT4L

DDIT4L: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Belongs to the DDIT4 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4q24

Cellular Component: cytoplasm

Biological Process: negative regulation of signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DDIT4L antibody

 Products by Pathway  Pathway Diagram
 TOR Signaling Pathway antibodies  TOR Signaling Pathway Diagram
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