• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

DNMT3A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6376497

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates… More details

$1165 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNMT3A, Polyclonal Antibody
Full Product Name
DNMT3A (DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA Methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA) (MaxLight 490)
Product Gene Name
anti-DNMT3A antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human DNMT3A.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
102kDa
Chromosome Location
Chromosome: 2; NC_000002.11 (25451421..25565459, complement). Location: 2p23
OMIM
602769
3D Structure
ModBase 3D Structure for Q9Y6K1
Immunogen
Full length human DNMT3A, aa1-912 (NP_072046.2).
Immunogen Sequence
MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-DNMT3A antibody

Antibodies; Enzymes; Methyltransferase
Applications Tested/Suitable for anti-DNMT3A antibody
Western Blot (WB)
Application Notes for anti-DNMT3A antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-DNMT3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNMT3A purchase

MBS6376497 is an antibody targeting DNMT3A. Also known as DNMT3A (DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA Methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA) (MaxLight 490). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DNMT3A. It may not necessarily be applicable to this product.

NCBI GI #
12751473
NCBI GeneID
1788
NCBI Accession #
NP_072046.2
UniProt Primary Accession #
Q9Y6K1
UniProt Secondary Accession #
Q86TE8; Q86XF5; Q8IZV0; Q8WXU9; E9PEB8
UniProt Related Accession #
Q9Y6K1
GenBank Nucleotide #
NM_022552.3
NCBI Official Full Name
DNA (cytosine-5)-methyltransferase 3A isoform a
NCBI Official Synonym Full Names
DNA (cytosine-5-)-methyltransferase 3 alpha
NCBI Official Symbol
DNMT3A
NCBI Official Synonym Symbols
DNMT3A2; M.HsaIIIA
UniProt Protein Name
DNA (cytosine-5)-methyltransferase 3A
UniProt Synonym Protein Names
DNA methyltransferase HsaIIIA
Protein Family
DNA
UniProt Gene Name
DNMT3A
UniProt Synonym Gene Names
Dnmt3a; DNA MTase HsaIIIA; M.HsaIIIA
UniProt Entry Name
DNM3A_HUMAN
NCBI Protein Information
DNA (cytosine-5)-methyltransferase 3A; DNA (cytosine-5)-methyltransferase 3A; DNA MTase HsaIIIA; DNA cytosine methyltransferase 3A2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DNMT3A antibody

 Reference Product  PubMed Publications
 DNMT3B antibody  >431 publications with DNMT3A and DNMT3B
 DNMT1 antibody  >413 publications with DNMT3A and DNMT1
 DNMT3L antibody  >98 publications with DNMT3A and DNMT3L
 EZH2 antibody  >37 publications with DNMT3A and EZH2
 MYC antibody  >13 publications with DNMT3A and MYC
 SUV39H1 antibody  >11 publications with DNMT3A and SUV39H1
 UHRF1 antibody  >9 publications with DNMT3A and UHRF1
 SETDB1 antibody  >5 publications with DNMT3A and SETDB1
 CBX5 antibody  >1 publications with DNMT3A and CBX5
 ZBTB17 antibody  >1 publications with DNMT3A and ZBTB17

Pathways associated with anti-DNMT3A antibody

 Products by Pathway  Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Methionine Degradation Pathway antibodies  Methionine Degradation Pathway Diagram
 Methionine Degradation Pathway antibodies  Methionine Degradation Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 One Carbon Metabolism Pathway antibodies  One Carbon Metabolism Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Repression Pathway antibodies  Validated Targets Of C-MYC Transcriptional Repression Pathway Diagram

Diseases associated with anti-DNMT3A antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >260 publications with DNMT3A and Neoplasms
 Drug Toxicity Antibodies  >32 publications with DNMT3A and Drug Toxicity
 Breast Neoplasms Antibodies  >24 publications with DNMT3A and Breast Neoplasms
 Liver Diseases Antibodies  >23 publications with DNMT3A and Liver Diseases
 Genital Diseases, Male Antibodies  >20 publications with DNMT3A and Genital Diseases, Male
 Carcinoma, Hepatocellular Antibodies  >18 publications with DNMT3A and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >18 publications with DNMT3A and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >18 publications with DNMT3A and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >16 publications with DNMT3A and Lung Neoplasms
 Prostatic Neoplasms Antibodies  >13 publications with DNMT3A and Prostatic Neoplasms

Organs/Tissues associated with anti-DNMT3A antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >95 publications with DNMT3A and Blood
 Brain Antibodies  >63 publications with DNMT3A and Brain
 Liver Antibodies  >50 publications with DNMT3A and Liver
 Embryonic Tissue Antibodies  >33 publications with DNMT3A and Embryonic Tissue
 Lung Antibodies  >28 publications with DNMT3A and Lung
 Testis Antibodies  >25 publications with DNMT3A and Testis
 Prostate Antibodies  >22 publications with DNMT3A and Prostate
 Nerve Antibodies  >20 publications with DNMT3A and Nerve
 Kidney Antibodies  >15 publications with DNMT3A and Kidney
 Ovary Antibodies  >15 publications with DNMT3A and Ovary
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000