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H2AFJ Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6305226

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
H2AFJ, Polyclonal Antibody
Full Product Name
H2AFJ, NT (H2AFJ, Histone H2A.J) (MaxLight 650)
Product Gene Name
anti-H2AFJ antibody
Product Synonym Names
H2AFJ; Histone H2A.J
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
16,110 Da
3D Structure
ModBase 3D Structure for Q9BTM1
Immunogen
H2AFJ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human H2AFJ.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-H2AFJ antibody

Antibodies; Histones
Applications Tested/Suitable for anti-H2AFJ antibody
Western Blot (WB), FLISA
Application Notes for anti-H2AFJ antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-H2AFJ antibody

Yao, J., et al. Cancer Res. 66(8):4065-4078(2006). de Wit, N.J., et al. Br. J. Cancer 92(12):2249-2261(2005). Chadwick, B.P., et al. Hum. Mol. Genet. 10(10):1101-1113(2001).

Other Notes

Small volumes of anti-H2AFJ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for H2AFJ purchase

MBS6305226 is an antibody targeting H2AFJ. Also known as H2AFJ, NT (H2AFJ, Histone H2A.J) (MaxLight 650). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for H2AFJ. It may not necessarily be applicable to this product.

NCBI GI #
29553970
NCBI GeneID
55766
NCBI Accession #
NP_808760.1
UniProt Primary Accession #
Q9BTM1
UniProt Secondary Accession #
Q9NV63
UniProt Related Accession #
Q9BTM1
GenBank Nucleotide #
NM_177925.3
NCBI Official Full Name
histone H2A.J
NCBI Official Synonym Full Names
H2A histone family, member J
NCBI Official Symbol
H2AFJ
NCBI Official Synonym Symbols
H2AJ
UniProt Protein Name
Histone H2A.J
Protein Family
Histone
UniProt Gene Name
H2AFJ
UniProt Synonym Gene Names
H2a/j
UniProt Entry Name
H2AJ_HUMAN
NCBI Protein Information
histone H2A.J; H2a/j; buforin I

UniProt Comments for H2AFJ

H2AFJ: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12p12.3

Cellular Component: nucleosome; nucleus

Molecular Function: DNA binding; protein heterodimerization activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-H2AFJ antibody

 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Systemic Lupus Erythematosus Pathway antibodies  Systemic Lupus Erythematosus Pathway Diagram
 Systemic Lupus Erythematosus Pathway antibodies  Systemic Lupus Erythematosus Pathway Diagram

Organs/Tissues associated with anti-H2AFJ antibody

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >1 publications with H2AFJ and Lymph Node
 Skin Antibodies  >1 publications with H2AFJ and Skin
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