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HYAL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6308975

This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments… More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HYAL2, Polyclonal Antibody
Full Product Name
HYAL2, ID (HYAL2, LUCA2, Hyaluronidase-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2) (MaxLight 490)
Product Gene Name
Product Synonym Names
HYAL2; LUCA2; Hyaluronidase-2; Hyaluronoglucosaminidase-2; Lung carcinoma protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
53,860 Da
3D Structure
ModBase 3D Structure for Q12891
Immunogen
HYAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-157 amino acids from the Central region of human HYAL2.
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-HYAL2 antibody

Applications Tested/Suitable for anti-HYAL2 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-HYAL2 antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-HYAL2 antibody

Monzon, M.E., et al. J. Biol. Chem. 285(34):26126-26134(2010). Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010). de la Motte, C., et al. Am. J. Pathol. 174(6):2254-2264(2009). Nykopp, T.K., et al. BMC Cancer 9, 143 (2009): Miller, A.D., et al. Osteoarthr. Cartil. 14(12):1315-1317(2006).

Other Notes

Small volumes of anti-HYAL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HYAL2 purchase

MBS6308975 is an antibody targeting HYAL2. Also known as HYAL2, ID (HYAL2, LUCA2, Hyaluronidase-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2) (MaxLight 490). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HYAL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hyaluronidase-2
NCBI Official Synonym Full Names
hyaluronoglucosaminidase 2
NCBI Official Symbol
HYAL2
NCBI Official Synonym Symbols
LUCA2
UniProt Protein Name
Hyaluronidase-2
UniProt Synonym Protein Names
Hyaluronoglucosaminidase-2; Lung carcinoma protein 2; LuCa-2
UniProt Gene Name
HYAL2
UniProt Synonym Gene Names
LUCA2; Hyal-2; LuCa-2
NCBI Protein Information
hyaluronidase-2; hyal-2; PH20 homolog; PH-20 homolog; hyaluronidase 2; lysosomal hyaluronidase; lung carcinoma protein 2; hyaluronoglucosaminidase-2

UniProt Comments for HYAL2

Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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