Rabbit Anti-IDAS Polyclonal Antibody – Cat# MBS6309160

IDAS Antibody (N-term) western blot analysis in human uterus tissue lysate (35ug/lane).This demonstrates the IDAS antibody detected the IDAS protein (arrow).

IDAS Antibody – Rabbit Polyclonal

Name: IDAS Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6309160
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6309160

Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex By similarity. Plays a role in mitotic cell cycle progression by… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IDAS, Polyclonal Antibody

Full Product Name

IDAS, NT (MCI, IDAS, Multicilin, Protein Idas) (Azide free) (HRP)

Product Gene Name

anti-IDAS antibody

Product Synonym Gene Name

MCI

Product Synonym Names

MCI; IDAS; Multicilin; Protein Idas

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,720 Da

OMIM

614086

3D Structure

ModBase 3D Structure for D6RGH6

Immunogen

IDAS antibody is generated from rabbits immunized with a KLH conjugated synthetic between 19-46 amino acids selected from the N-terminal region of human IDAS.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-IDAS antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-IDAS antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-IDAS antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-IDAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IDAS purchase

MBS6309160 is an antibody targeting IDAS. Also known as IDAS, NT (MCI, IDAS, Multicilin, Protein Idas) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IDAS. It may not necessarily be applicable to this product.

NCBI GI #

299782571

NCBI GeneID

345643

NCBI Accession #

NP_001177716.1

UniProt Primary Accession #

D6RGH6

UniProt Secondary Accession #

C9JGY3; D6R920; F8KGQ8

UniProt Related Accession #

D6RGH6

GenBank Nucleotide #

NM_001190787.1

NCBI Official Full Name

multicilin

NCBI Official Synonym Full Names

multiciliate differentiation and DNA synthesis associated cell cycle protein

NCBI Official Symbol

MCIDAS

NCBI Official Synonym Symbols

MCI; IDAS; MCIN

UniProt Protein Name

Multicilin

UniProt Synonym Protein Names

Multiciliate differentiation and DNA synthesis-associated cell cycle protein; McIdas protein; Protein Idas

Protein Family

Multicilin

UniProt Gene Name

MCIDAS

UniProt Synonym Gene Names

IDAS; MCI; MCIN; McIdas protein

NCBI Protein Information

multicilin

NCBI Summary for IDAS

This gene encodes a member of the geminin family of proteins. The encoded nuclear protein is required for the generation of multiciliated cells in respiratory epithelium. Mutations in this gene cause a rare mucociliary clearance disorder associated with recurring respiratory infections in human patients, known as reduced generation of multiple motile cilia (RGMC). [provided by RefSeq, Sep 2016]

UniProt Comments for IDAS

Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).

Research Articles on IDAS

1. MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia.MCIDAS regulates CCNO and FOXJ1 expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-IDAS antibody

Disease Name	Pubmed Publications
Infertility Antibodies	>2 publications with IDAS and Infertility
Fibrosis Antibodies	>1 publications with IDAS and Fibrosis