• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IL-28 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9703694

IFNL2 encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
IL-28, Polyclonal Antibody
Full Product Name
IL-28 Polyclonal Antibody
Product Gene Name
Product Synonym Names
Rabbit Anti-IL-28 Polyclonal Antibody; IL28A; IFNL2; ZCYTO20; Interleukin-28A; IL-28A; Cytokine Zcyto20; Interferon lambda-2; IFN-lambda-2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; PBS Containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml (lot specific)
Specificity
IL-28 Polyclonal Antibody detects endogenous levels of IL-28 protein.
Preparation and Storage
Stable for one year at -20 degree C from date of shipment.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
OMIM
607401
3D Structure
ModBase 3D Structure for Q8IZJ0
Immunogen
Synthesized peptide derived from the C-terminal region of human IL-28
Applications Tested/Suitable for anti-IL-28 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes for anti-IL-28 antibody
WB: 1:500-1:2000
IHC-P: 1:100-1:300
ELISA: 1:20000

Western Blot (WB) of anti-IL-28 antibody

Fig.1. Western Blot analysis of MCF7 cells using IL-28 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.
Rabbit Anti-IL-28 Polyclonal Antibody – Cat# MBS9703694

Immunohistochemistry (IHC) of anti-IL-28 antibody

Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100.
Rabbit Anti-IL-28 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9703694

Immunohistochemistry (IHC) of anti-IL-28 antibody

Fig.3. Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100.
Rabbit Anti-IL-28 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9703694

Immunohistochemistry (IHC) of anti-IL-28 antibody

Fig.4. Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100.
Rabbit Anti-IL-28 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9703694

Immunohistochemistry (IHC) of anti-IL-28 antibody

Fig.5. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100.
Rabbit Anti-IL-28 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9703694

Immunohistochemistry (IHC) of anti-IL-28 antibody

Fig.6. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100.
Rabbit Anti-IL-28 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9703694

Other Notes

Small volumes of anti-IL-28 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-28 purchase

MBS9703694 is an antibody targeting IL-28. Also known as IL-28 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-28. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon lambda-2
NCBI Official Synonym Full Names
interferon lambda 2
NCBI Official Symbol
IFNL2
NCBI Official Synonym Symbols
IL28A; IL-28A
UniProt Protein Name
Interferon lambda-2
UniProt Synonym Protein Names
Cytokine Zcyto20; Interleukin-28A
UniProt Gene Name
IFNL2
UniProt Synonym Gene Names
IL28A; ZCYTO20; IFN-lambda-2; IL-28A
UniProt Entry Name
IFNL2_HUMAN
NCBI Protein Information
interferon lambda-2

NCBI Summary for IL-28

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for IL-28

IL28A: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 19q13.13

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: positive regulation of immune response; mucosal immune response; JAK-STAT cascade; defense response to virus
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000