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P4HTM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9133628
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The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
P4HTM, Polyclonal Antibody
Full Product Name
P4HTM Polyclonal Antibody
Product Gene Name
Product Synonym Names
EGLN4; HIFPH4; P4H-TM; PH-4; PH4; PHD4
Immunogen Sequence
RQRVLRLTRL SPEIVELSEP LQVVRYGEGG HYHAHVDSGP VYPETICSHT KLVANESVPF ETSCRQVSPN WGLPSILRPG TPMTQAQPCT VGVPLGMGPG DHWVIPVSPW EHPQLGTCSV PPLPYSYMTV LFYLNNVTGG GETVFPVADN RTYDEMSLIQ DDVDLRDTRR HCDKGNLRVK PQQGTAVFWY NYLPDGQGWV GDVDDYSLHG GCLVTRGTKW IANNWINVDP SRARQALFQQ EMARLAREGG TDSQP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
47kDa/56kDa/63kDa
OMIM
AY198406 mRNA
3D Structure
ModBase 3D Structure for Q9NXG6
Immunogen
Recombinant protein of human P4HTM
Immunogen Species
Human
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Endoplasmic reticulum membrane, Single-pass type II membrane protein

Product Categories/Family for anti-P4HTM antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-P4HTM antibody
Immunofluorescence (IF)
Application Notes for anti-P4HTM antibody
IF: 1:50 - 1:200

Immunofluorescence (IF) of anti-P4HTM antibody

Immunofluorescence analysis of HeLa cells using P4HTM antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-P4HTM Polyclonal Antibody – Cat# MBS9133628

Other Notes

Small volumes of anti-P4HTM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P4HTM purchase

MBS9133628 is an antibody targeting P4HTM. Also known as P4HTM Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for P4HTM. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transmembrane prolyl 4-hydroxylase isoform c
NCBI Official Synonym Full Names
prolyl 4-hydroxylase, transmembrane
NCBI Official Symbol
P4HTM
NCBI Official Synonym Symbols
PH4; PH-4; PHD4; EGLN4; HIFPH4; P4H-TM
UniProt Protein Name
Transmembrane prolyl 4-hydroxylase
UniProt Synonym Protein Names
Hypoxia-inducible factor prolyl hydroxylase 4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4
UniProt Gene Name
P4HTM
UniProt Synonym Gene Names
PH4; P4H-TM; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4
NCBI Protein Information
transmembrane prolyl 4-hydroxylase

UniProt Comments for P4HTM

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-P4HTM antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with P4HTM and Muscle
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