Rabbit Anti-PDGFD Polyclonal Antibody – Cat# MBS9148404

Western blot analysis of lysates from Mouse heart using PDGFD Rabbit pAb (MBS9148404) at 1:2000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45s.

PDGFD Antibody – Rabbit Polyclonal

Name: PDGFD Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9148404
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9148404

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PDGFD, Polyclonal Antibody

Full Product Name

PDGFD Rabbit pAb

Product Gene Name

anti-PDGFD antibody

Product Synonym Names

IEGF; SCDGFB; MSTP036; SCDGF-B; PDGFD

Immunogen Sequence

RDTSATPQSA SIKALRNANL RRDESNHLTD LYRRDETIQV KGNGYVQSPR FPNSYPRNLL LTWRLHSQEN TRIQLVFDNQ FGLEEAENDI CRYDFVEVED ISETSTIIRG RWCGHKEVPP RIKSRTNQIK ITFKSDDYFV AKPGFKIYYS LLEDFQPAAA SETNWESVTS SISGVSYNSP SVTDPTLIAD ALDKKIAEFD TVEDLLKYFN PESWQEDLEN MYLDTPRYRG RSYHDRKSKV DLDRLNDDAK RYSCTPRNYS VNIREELKLA NVVFFPRCLL VQR

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

Molecular Weight

Calculated MW: 43kDa
Observed MW: 35kDa

OMIM

609673

3D Structure

ModBase 3D Structure for Q9GZP0

Cross Reactivity

Mouse

Immunogen

Recombinant Protein corresponding to a sequence within amino acids 19-307 of human PDGFD(NP_079484.1).

Product Categories/Family for anti-PDGFD antibody

Cancer; Signal Transduction; Cell Biology Developmental Biology; Growth factors; Neuroscience; Cardiovascular; Angiogenesis; Antibodies

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PDGFD antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-PDGFD antibody

WB: 1:1000-1:5000
ELISA: Recommended starting concentration is 1ug/mL.
Please optimize the concentration based on your specific assay requirements.

Other Notes

Small volumes of anti-PDGFD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDGFD purchase

MBS9148404 is an antibody targeting PDGFD. Also known as PDGFD Rabbit pAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDGFD. It may not necessarily be applicable to this product.

NCBI GI #

15451921

NCBI GeneID

80310

NCBI Accession #

NP_149126.1

UniProt Primary Accession #

Q9GZP0

UniProt Secondary Accession #

Q9BWV5; A8K9T6

UniProt Related Accession #

Q9GZP0

GenBank Nucleotide #

NM_033135.3

UniProt Protein Name

Platelet-derived growth factor D

UniProt Synonym Protein Names

Iris-expressed growth factor; Spinal cord-derived growth factor B

Protein Family

Platelet-derived growth factor

UniProt Gene Name

PDGFD

UniProt Synonym Gene Names

IEGF; SCDGFB; PDGF-D; SCDGF-B; PDGFD latent form

UniProt Entry Name

PDGFD_HUMAN

UniProt Comments for PDGFD

PDGFD: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Oncoprotein

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: Golgi membrane; endoplasmic reticulum lumen; extracellular region

Molecular Function: growth factor activity; platelet-derived growth factor receptor binding

Biological Process: multicellular organismal development; positive regulation of cell division; platelet-derived growth factor receptor signaling pathway; regulation of peptidyl-tyrosine phosphorylation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PDGFD antibody

Reference Product	PubMed Publications
PDGFRB antibody	>32 publications with PDGFD and PDGFRB
PDGFRA antibody	>22 publications with PDGFD and PDGFRA
FLT1 antibody	>3 publications with PDGFD and FLT1
VEGFA antibody	>2 publications with PDGFD and VEGFA
FGFR1 antibody	>1 publications with PDGFD and FGFR1
EGFR antibody	>1 publications with PDGFD and EGFR

Pathways associated with anti-PDGFD antibody

Products by Pathway	Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Gap Junction Pathway antibodies	Gap Junction Pathway Diagram
Gap Junction Pathway antibodies	Gap Junction Pathway Diagram
Melanoma Pathway antibodies	Melanoma Pathway Diagram
Melanoma Pathway antibodies	Melanoma Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram
Prostate Cancer Pathway antibodies	Prostate Cancer Pathway Diagram

Diseases associated with anti-PDGFD antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>10 publications with PDGFD and Kidney Diseases
Fibrosis Antibodies	>9 publications with PDGFD and Fibrosis
Brain Diseases Antibodies	>8 publications with PDGFD and Brain Diseases
Disease Models, Animal Antibodies	>6 publications with PDGFD and Disease Models, Animal
Cell Transformation, Neoplastic Antibodies	>4 publications with PDGFD and Cell Transformation, Neoplastic
Inflammation Antibodies	>4 publications with PDGFD and Inflammation
Coronary Artery Disease Antibodies	>4 publications with PDGFD and Coronary Artery Disease
Heart Diseases Antibodies	>3 publications with PDGFD and Heart Diseases
Liver Cirrhosis Antibodies	>2 publications with PDGFD and Liver Cirrhosis
Liver Diseases Antibodies	>2 publications with PDGFD and Liver Diseases

Organs/Tissues associated with anti-PDGFD antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>22 publications with PDGFD and Vascular
Kidney Antibodies	>13 publications with PDGFD and Kidney
Prostate Antibodies	>11 publications with PDGFD and Prostate
Brain Antibodies	>6 publications with PDGFD and Brain
Heart Antibodies	>5 publications with PDGFD and Heart
Connective Tissue Antibodies	>4 publications with PDGFD and Connective Tissue
Lung Antibodies	>4 publications with PDGFD and Lung
Ovary Antibodies	>4 publications with PDGFD and Ovary
Eye Antibodies	>4 publications with PDGFD and Eye
Lymph Node Antibodies	>3 publications with PDGFD and Lymph Node