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PHC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3220116

This is a rabbit polyclonal antibody against PHC3. It was validated on Western BlotTarget Description: PHC3 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PHC3, Polyclonal Antibody
Full Product Name
PHC3 Antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
PHC3; EDR3; PH3;
Immunogen Sequence
Synthetic peptide located within the following region: LSRWNRKPDN QSLGHRGRRP SGPDGAAREH ILRQLPITYP SAEEDLASHE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
PHC3 peptide (MBS3244945) is used for blocking the activity of PHC3 antibody (MBS3220116)
Molecular Weight
108kDa
3D Structure
ModBase 3D Structure for Q8NDX5
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC3
Applications Tested/Suitable for anti-PHC3 antibody
Western Blot (WB)

Western Blot (WB) of anti-PHC3 antibody

Host: Rabbit
Target Name: PHC3
Sample Type: 293T Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-PHC3 Polyclonal Antibody – Cat# MBS3220116

Other Notes

Small volumes of anti-PHC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PHC3 purchase

MBS3220116 is an antibody targeting PHC3. Also known as PHC3 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PHC3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
polyhomeotic homolog 3
NCBI Official Symbol
PHC3
NCBI Official Synonym Symbols
EDR3; HPH3
UniProt Protein Name
Polyhomeotic-like protein 3
UniProt Synonym Protein Names
Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3
UniProt Gene Name
PHC3
UniProt Synonym Gene Names
EDR3; PH3; hPH3
UniProt Entry Name
PHC3_HUMAN
NCBI Protein Information
polyhomeotic-like protein 3

UniProt Comments for PHC3

PHC3: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; PcG protein complex; nucleus; actin cytoskeleton

Molecular Function: DNA binding; zinc ion binding

Biological Process: multicellular organismal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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