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PLA2G4E Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6458187

MBS6458187 is an antibody targeting PLA2G4E. Also known as PLA2G4E (Cytosolic Phospholipase A2 epsilon, cPLA2-epsilon, Phospholipase A2 group IVE, PLA2G4E) (APC). Reactive in Human. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLA2G4E, Polyclonal Antibody
Full Product Name
PLA2G4E (Cytosolic Phospholipase A2 epsilon, cPLA2-epsilon, Phospholipase A2 group IVE, PLA2G4E) (APC)
Product Gene Name
anti-PLA2G4E antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes human PLA2G4E.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
97,570 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (42273780..42342901, complement). Location: 15q15.1
3D Structure
ModBase 3D Structure for Q3MJ16
Immunogen
Synthetic peptide corresponding to PLA2G4E.
Conjugate
APC
Note
Preservative Free

Product Categories/Family for anti-PLA2G4E antibody

Antibodies; Enzymes; Phospholipase
Applications Tested/Suitable for anti-PLA2G4E antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-PLA2G4E antibody
IHC: 1:50-1:100
WB: 1:500-1:1000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PLA2G4E antibody

1. Ota T., et al. Nat. Genet. 36:40-45(2004).2. Zody M.C., et al. Nature 440:671-675(2006).

Other Notes

Small volumes of anti-PLA2G4E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G4E. It may not necessarily be applicable to this product.

NCBI GI #
331284217
NCBI GeneID
123745
NCBI Accession #
NP_001193599.1
UniProt Primary Accession #
Q3MJ16
UniProt Secondary Accession #
Q6ZSC0
UniProt Related Accession #
Q3MJ16
GenBank Nucleotide #
NM_001206670.1
NCBI Official Full Name
cytosolic phospholipase A2 epsilon
NCBI Official Synonym Full Names
phospholipase A2, group IVE
NCBI Official Symbol
PLA2G4E
UniProt Protein Name
Cytosolic phospholipase A2 epsilon
UniProt Synonym Protein Names
Phospholipase A2 group IVE
Protein Family
Cytosolic phospholipase
UniProt Gene Name
PLA2G4E
UniProt Synonym Gene Names
cPLA2-epsilon
UniProt Entry Name
PA24E_HUMAN
NCBI Protein Information
cytosolic phospholipase A2 epsilon; cPLA2-epsilon

UniProt Comments for PLA2G4E

PLA2G4E: a calcium-dependent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Selectively hydrolyzes glycerophospholipids in the sn-2 position. Translocates to lysosomal membranes in a calcium-dependent fashion. The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca2+. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Phospholipase; Lipid Metabolism - linoleic acid; EC 3.1.1.4; Lipid Metabolism - ether lipid; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: lysosomal membrane; cytosol

Molecular Function: phospholipase A2 activity; metal ion binding

Biological Process: phospholipid catabolic process; phospholipid metabolic process; glycerophospholipid biosynthetic process
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Research Articles on PLA2G4E

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLA2G4E antibody

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Acyl Chain Remodelling Of PI Pathway antibodies  Acyl Chain Remodelling Of PI Pathway Diagram
 Acyl Chain Remodelling Of PS Pathway antibodies  Acyl Chain Remodelling Of PS Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
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