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REC8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9510107

MBS9510107 is an antibody targeting REC8. Also known as REC8 Antibody. Reactive in Human. Host: Rabbit. More details

$335 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
REC8, Polyclonal Antibody
Full Product Name
REC8 Antibody
Product Gene Name
Product Synonym Names
Meiotic recombination protein REC8 homolog; Cohesin Rec8p; REC8; REC8L1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
1 mg/ml (lot specific)
Specificity
REC8 Antibody detects endogenous levels of REC8.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Molecular Weight
62 kDa
OMIM
AF006264 mRNA
3D Structure
ModBase 3D Structure for O95072
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human REC8.
Immunogen Range
137-186
Applications Tested/Suitable for anti-REC8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-REC8 antibody
WB: 1:500~1:1000
ELISA: 1:10000

Western Blot (WB) of anti-REC8 antibody

Western blot analysis of the lysates from HT-29 cells using REC8 antibody.
Rabbit Anti-REC8 Polyclonal Antibody – Cat# MBS9510107

Other Notes

Small volumes of anti-REC8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for REC8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
meiotic recombination protein REC8 homolog
NCBI Official Synonym Full Names
REC8 meiotic recombination protein
NCBI Official Symbol
REC8
NCBI Official Synonym Symbols
Rec8p; REC8L1; HR21spB
UniProt Protein Name
Meiotic recombination protein REC8 homolog
UniProt Synonym Protein Names
Cohesin Rec8p
UniProt Gene Name
REC8
UniProt Synonym Gene Names
REC8L1
NCBI Protein Information
meiotic recombination protein REC8 homolog

NCBI Summary for REC8

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for REC8

Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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