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REV3L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8566682

The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
REV3L, Polyclonal Antibody
Full Product Name
REV3L Polyclonal Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
344kDa; 352kDa
OMIM
602776
3D Structure
ModBase 3D Structure for O60673
Immunogen
Recombinant protein of human REV3L (NP_002903.3).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-REV3L antibody
Western Blot (WB)
Application Notes for anti-REV3L antibody
WB: 1:500-1:2000

Other Notes

Small volumes of anti-REV3L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for REV3L purchase

MBS8566682 is an antibody targeting REV3L. Also known as REV3L Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for REV3L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA polymerase zeta catalytic subunit isoform a
NCBI Official Synonym Full Names
REV3 like, DNA directed polymerase zeta catalytic subunit
NCBI Official Symbol
REV3L
NCBI Official Synonym Symbols
POLZ; REV3
UniProt Protein Name
DNA polymerase zeta catalytic subunit
UniProt Synonym Protein Names
Protein reversionless 3-like
UniProt Gene Name
REV3L
UniProt Synonym Gene Names
POLZ; REV3; REV3-like; hREV3
UniProt Entry Name
DPOLZ_HUMAN
NCBI Protein Information
DNA polymerase zeta catalytic subunit

UniProt Comments for REV3L

REV3: the DNA polymerase zeta catalytic subunit. Catalyzes the production of N diphosphate + {DNA}N from N deoxynucleoside triphosphate. Involved in translesion synthesis and required for the production of UV- and other DNA fork-blocking-induced mutations, as well as the majority of spontaneous mutations.

Protein type: Transferase; EC 2.7.7.7; DNA replication

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: nucleoplasm; zeta DNA polymerase complex; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; metal ion binding; 4 iron, 4 sulfur cluster binding; DNA-directed DNA polymerase activity; nucleotide binding

Biological Process: error-prone postreplication DNA repair; DNA-dependent DNA replication; DNA repair
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-REV3L antibody

 Reference Product  PubMed Publications
 MAD2L2 antibody  >15 publications with REV3L and MAD2L2
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