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RMI1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6342342

RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM]. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RMI1, Polyclonal Antibody
Full Product Name
RMI1, NT (RMI1, C9orf76, RecQ-mediated genome instability protein 1, BLM-associated protein of 75kD, FAAP75) (MaxLight 550)
Product Gene Name
Product Synonym Names
RMI1; C9orf76; RecQ-mediated genome instability protein 1; BLM-associated protein of 75kD; FAAP75
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
70,144 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (86595321..86618989). Location: 9q21.32
OMIM
610404
3D Structure
ModBase 3D Structure for Q9H9A7
Immunogen
RMI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human RMI1.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-RMI1 antibody

Applications Tested/Suitable for anti-RMI1 antibody
Western Blot (WB), FLISA
Application Notes for anti-RMI1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RMI1 antibody

Yang, J., et al. J. Biol. Chem. 285(28):21426-21436(2010). Frank, B., et al. Carcinogenesis 31(3):442-445(2010). Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010): Luedeke, M., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3030-3035(2009). Broberg, K., et al. BMC Cancer 9, 140 (2009).

Other Notes

Small volumes of anti-RMI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RMI1 purchase

MBS6342342 is an antibody targeting RMI1. Also known as RMI1, NT (RMI1, C9orf76, RecQ-mediated genome instability protein 1, BLM-associated protein of 75kD, FAAP75) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RMI1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
recQ-mediated genome instability protein 1
NCBI Official Synonym Full Names
RecQ mediated genome instability 1
NCBI Official Symbol
RMI1
NCBI Official Synonym Symbols
BLAP75; FAAP75; C9orf76; RP11-346I8.1
UniProt Protein Name
RecQ-mediated genome instability protein 1
UniProt Synonym Protein Names
BLM-associated protein of 75 kDa; BLAP75; FAAP75
UniProt Gene Name
RMI1
UniProt Synonym Gene Names
C9orf76; BLAP75
UniProt Entry Name
RMI1_HUMAN
NCBI Protein Information
recQ-mediated genome instability protein 1; BLM-associated protein 75 kDa; BLM-associated polypeptide, 75 kDa; RMI1, RecQ mediated genome instability 1, homolog; homolog of yeast RecQ-mediated genome instability 1 (RMI1)

NCBI Summary for RMI1

RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM, Mar 2008]

UniProt Comments for RMI1

RMI1: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. Belongs to the RMI1 family.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 9q21.32

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: multicellular organism growth; response to glucose stimulus; DNA replication; glucose homeostasis; reduction of food intake in response to dietary excess
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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