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RNASEH2C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7103259

Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RNASEH2C, Polyclonal Antibody
Full Product Name
RNASEH2C Antibody
Product Gene Name
Product Synonym Names
Ribonuclease H2 subunit C; RNase H2 subunit C; Aicardi-Goutieres syndrome 3 protein; AGS3; RNase H1 small subunit; Ribonuclease HI subunit C; RNASEH2C; AYP1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: RNASEH2C (MBS7103259)
HRP Conjugated Antibody: RNASEH2C (MBS7103260)
Matching Pairs
Unconjugated Antibody: RNASEH2C (MBS7103259)
FITC Conjugated Antibody: RNASEH2C (MBS7103261)
Molecular Weight
17,840 Da
OMIM
AF312034 mRNA
3D Structure
ModBase 3D Structure for Q8TDP1
Immunogen
Recombinant Human Ribonuclease H2 subunit C protein (1-164AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RNASEH2C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-RNASEH2C antibody
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-RNASEH2C antibody

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate
All lanes: RNASEH2C antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 18 KDa
Observed band size: 18 KDa
Rabbit Anti-RNASEH2C Polyclonal Antibody – Cat# MBS7103259

Immunohistochemistry (IHC) of anti-RNASEH2C antibody

Immunohistochemistry of paraffin-embedded human skin tissue using MBS7103259 at dilution of 1:100
Rabbit Anti-RNASEH2C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7103259

Immunohistochemistry (IHC) of anti-RNASEH2C antibody

Immunofluorescent analysis of Hela cells using MBS7103259 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-RNASEH2C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7103259

Other Notes

Small volumes of anti-RNASEH2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNASEH2C purchase

MBS7103259 is an antibody targeting RNASEH2C. Also known as RNASEH2C Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RNASEH2C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ribonuclease H2 subunit C
NCBI Official Synonym Full Names
ribonuclease H2 subunit C
NCBI Official Symbol
RNASEH2C
NCBI Official Synonym Symbols
AGS3; AYP1
UniProt Protein Name
Ribonuclease H2 subunit C
UniProt Synonym Protein Names
Aicardi-Goutieres syndrome 3 protein; AGS3; RNase H1 small subunit; Ribonuclease HI subunit C
Protein Family
UniProt Gene Name
RNASEH2C
UniProt Synonym Gene Names
AYP1; RNase H2 subunit C; AGS3
NCBI Protein Information
ribonuclease H2 subunit C

NCBI Summary for RNASEH2C

This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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