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SELV Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6345955

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SELV, Polyclonal Antibody
Full Product Name
SELV, CT (SELV, Selenoprotein V) (APC)
Product Gene Name
anti-SELV antibody
Product Synonym Names
SELV; Selenoprotein V
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
36,800 Da
OMIM
607919
3D Structure
ModBase 3D Structure for P59797
Immunogen
SELV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-332 amino acids from the C-terminal region of human SELV.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-SELV antibody

Antibodies; Selenoprotein
Applications Tested/Suitable for anti-SELV antibody
Flow Cytometry (FC/FACS), FLISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-SELV antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
IF: 1:10-50
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SELV antibody

SELV Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SELV antibody detected the SELV protein (arrow).
Rabbit Anti-SELV Polyclonal Antibody – Cat# MBS6345955

Immunohistochemistry (IHC) of anti-SELV antibody

SELV Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SELV Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-SELV Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6345955

Flow Cytometry (FC/FACS) of anti-SELV antibody

SELV Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-SELV Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6345955

Immunofluorescence (IF) of anti-SELV antibody

Confocal immunofluorescent analysis of SELV Antibody (C-term) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-SELV Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6345955

Product References and Citations for anti-SELV antibody

Kryukov, G.V., et al. Science 300(5624):1439-1443(2003).

Other Notes

Small volumes of anti-SELV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SELV purchase

MBS6345955 is an antibody targeting SELV. Also known as SELV, CT (SELV, Selenoprotein V) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SELV. It may not necessarily be applicable to this product.

NCBI GI #
33186895
NCBI GeneID
348303
NCBI Accession #
NP_874363.1
UniProt Primary Accession #
P59797
UniProt Secondary Accession #
Q17RG5
UniProt Related Accession #
P59797
GenBank Nucleotide #
NM_182704.1
NCBI Official Full Name
selenoprotein V isoform 1
NCBI Official Synonym Full Names
selenoprotein V
NCBI Official Symbol
SELENOV
NCBI Official Synonym Symbols
SELV
UniProt Protein Name
Selenoprotein V
Protein Family
Selenoprotein
UniProt Gene Name
SELENOV
UniProt Synonym Gene Names
SelV
NCBI Protein Information
selenoprotein V

NCBI Summary for SELV

This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is specifically expressed in the testis. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2017]
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UniProt Comments for SELV

May be involved in a redox-related process.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SELV antibody

 Reference Product  PubMed Publications
 SELS antibody  >2 publications with SELV and SELS

Pathways associated with anti-SELV antibody

 Products by Pathway  Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram

Diseases associated with anti-SELV antibody

 Disease Name  Pubmed Publications
 Poisoning Antibodies  >3 publications with SELV and Poisoning
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