Rabbit Anti-SPAG6 Polyclonal Antibody – Cat# MBS6394851

Western Blot analysis of SPAG6 expression in transfected 293T cell line by SPAG6 polyclonal antibody. Lane 1: SPAG6 transfected lysate (55.5kD). Lane 2: Non-transfected lysate.

SPAG6 Antibody – Rabbit Polyclonal

Name: SPAG6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6394851
Price: 1165 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6394851

MBS6394851 is an antibody targeting SPAG6. Also known as SPAG6 (Sperm-associated Antigen 6, Protein PF16 Homolog, PF16, Repro-SA-1, Sperm Flagellar Protein) APC. Reactive in Human. Host: Rabbit. More details

$1165 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SPAG6, Polyclonal Antibody

Full Product Name

SPAG6 (Sperm-associated Antigen 6, Protein PF16 Homolog, PF16, Repro-SA-1, Sperm Flagellar Protein) APC

Product Gene Name

anti-SPAG6 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human SPAG6.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

605730

3D Structure

ModBase 3D Structure for O75602

Immunogen

Full length human SPAG6, aa1-509 (NP_036575.1).

Immunogen Sequence

MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYYSPGYSDTLLQRVDSYQPLNN

Conjugate

APC

Note

Preservative Free

Product Categories/Family for anti-SPAG6 antibody

Antibodies; Spermatogenesis; Testis Proteins

Applications Tested/Suitable for anti-SPAG6 antibody

Western Blot (WB)

Application Notes for anti-SPAG6 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-SPAG6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SPAG6. It may not necessarily be applicable to this product.

NCBI GI #

27262639

NCBI GeneID

9576

NCBI Accession #

NM_012443.2

UniProt Primary Accession #

O75602

UniProt Related Accession #

O75602

GenBank Nucleotide #

NM_012443.2

NCBI Official Full Name

Homo sapiens sperm associated antigen 6 (SPAG6), transcript variant 1, mRNA

NCBI Official Synonym Full Names

sperm associated antigen 6

NCBI Official Symbol

SPAG6

NCBI Official Synonym Symbols

pf16; CT141; FAP194; CFAP194; Repro-SA-1

UniProt Protein Name

Sperm-associated antigen 6

UniProt Synonym Protein Names

Protein PF16 homolog; Repro-SA-1; Sperm flagellar protein

Protein Family

Sperm-associated antigen

UniProt Gene Name

SPAG6

UniProt Synonym Gene Names

PF16

UniProt Entry Name

SPAG6_HUMAN

NCBI Protein Information

sperm-associated antigen 6

NCBI Summary for SPAG6

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Research Articles on SPAG6

1. Upregulation of SPAG6 is associated with Myelodysplastic Syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.