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SPNS2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2402085

SPNS2 antibody is an unconjugated rabbit polyclonal antibody to SPNS2 (aa71-120) from human. It is reactive with human, mouse, bat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication. More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SPNS2, Polyclonal Antibody
Full Product Name
SPNS2 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Product Gene Name
anti-SPNS2 antibody
Product Synonym Names
IHC-plus SPNS2 Antibody (aa71-120); SPNS2; Protein spinster homolog 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide, 2% sucrose
Purity/Purification
Immunoaffinity purified
Concentration
0.5mg/ml (lot specific)
Specificity
Human SPNS2
Preparation and Storage
Short term: Store at 2-8 degree C. Long term: Aliquot and store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
58,044 Da
OMIM
612584
3D Structure
ModBase 3D Structure for Q8IVW8
Target
Human SPNS2
Immunogen
Synthetic peptide located between aa71-120 of human SPNS2 (Q8IVW8, NP_001118230). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bat, Pig (100%); Galago, Rat (92%); Rabbit (91%); Mouse (84%).
Conjugation
Unconjugated
Epitope
aa71-120
Applications Tested/Suitable for anti-SPNS2 antibody
Immunohistochemistry (IHC), Immunohistochemistry-Paraffin (IHC-P), Western Blot (WB)
Application Notes for anti-SPNS2 antibody
IHC-P: 5ug/ml
WB: 0.2-1ug/ml
Western Blot: Suggested dilution at 1ug/ml in 5% skim milk/PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000-100,000 as secondary antibody.

Western Blot (WB) of anti-SPNS2 antibody

SPNS2 Antibody-SPNS2 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Rabbit Anti-SPNS2 Polyclonal Antibody – Cat# MBS2402085

Immunohistochemistry (IHC) of anti-SPNS2 antibody

SPNS2 Antibody-Anti-SPNS2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Rabbit Anti-SPNS2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2402085

Other Notes

Small volumes of anti-SPNS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SPNS2 purchase

MBS2402085 is an antibody targeting SPNS2. Also known as SPNS2 Rabbit anti-Human Polyclonal (aa71-120) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SPNS2. It may not necessarily be applicable to this product.

NCBI GI #
185136021
NCBI GeneID
124976
NCBI Accession #
NP_001118230.1
UniProt Primary Accession #
Q8IVW8
UniProt Secondary Accession #
B9A1T3
UniProt Related Accession #
Q8IVW8
GenBank Nucleotide #
NM_001124758.1
NCBI Official Full Name
protein spinster homolog 2
NCBI Official Synonym Full Names
spinster homolog 2 (Drosophila)
NCBI Official Symbol
SPNS2
UniProt Protein Name
Protein spinster homolog 2
Protein Family
Protein spinster
UniProt Gene Name
SPNS2
UniProt Entry Name
SPNS2_HUMAN
NCBI Protein Information
protein spinster homolog 2

UniProt Comments for SPNS2

SPNS2: Sphingolipid transporter required for migration of myocardial precursors. Transports sphingosine 1-phosphate (S1P), a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration. Belongs to the major facilitator (TC 2.A.1) superfamily. Spinster (TC 2.A.1.49) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: integral to membrane; lysosomal membrane; vesicle

Molecular Function: sphingolipid transporter activity

Biological Process: B cell homeostasis; lipid transport; locomotion; lymph node development; regulation of eye pigmentation; regulation of humoral immune response; sphingolipid metabolic process; T cell homeostasis; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SPNS2 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >2 publications with SPNS2 and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >2 publications with SPNS2 and Congenital Abnormalities
 Heart Diseases Antibodies  >1 publications with SPNS2 and Heart Diseases
 Heart Defects, Congenital Antibodies  >1 publications with SPNS2 and Heart Defects, Congenital

Organs/Tissues associated with anti-SPNS2 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with SPNS2 and Bone
 Blood Antibodies  >3 publications with SPNS2 and Blood
 Bone Marrow Antibodies  >2 publications with SPNS2 and Bone Marrow
 Heart Antibodies  >2 publications with SPNS2 and Heart
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