Rabbit Anti-STAG1 Polyclonal Antibody – Cat# MBS6351663

STAG1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the STAG1 antibody detected the STAG1 protein (arrow).

STAG1 Antibody – Rabbit Polyclonal

Name: STAG1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6351663
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6351663

This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

STAG1, Polyclonal Antibody

Full Product Name

STAG1, ID (STAG1, SA1, Cohesin subunit SA-1, SCC3 homolog 1, Stromal antigen 1) (PE)

Product Gene Name

anti-STAG1 antibody

Product Synonym Names

STAG1; SA1; Cohesin subunit SA-1; SCC3 homolog 1; Stromal antigen 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

140,090 Da

OMIM

604358

3D Structure

ModBase 3D Structure for Q8WVM7

Immunogen

STAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-568 amino acids from the Central region of human STAG1.

Conjugate

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-STAG1 antibody

Antibodies; Cell Division Cycle (CDC)

Applications Tested/Suitable for anti-STAG1 antibody

Western Blot (WB), FLISA

Application Notes for anti-STAG1 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-STAG1 antibody

Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009): Canudas, S., et al. J. Cell Biol. 187(2):165-173(2009). Rubio, E.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(24):8309-8314(2008). Watrin, E., et al. Curr. Biol. 16(9):863-874(2006). Losada, A., et al. J. Cell. Sci. 118 (PT 10), 2133-2141 (2005).

Other Notes

Small volumes of anti-STAG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAG1 purchase

MBS6351663 is an antibody targeting STAG1. Also known as STAG1, ID (STAG1, SA1, Cohesin subunit SA-1, SCC3 homolog 1, Stromal antigen 1) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STAG1. It may not necessarily be applicable to this product.

NCBI GI #

62243696

NCBI GeneID

10274

NCBI Accession #

NP_005853.2

UniProt Primary Accession #

Q8WVM7

UniProt Secondary Accession #

O00539; Q6P275

UniProt Related Accession #

Q8WVM7

GenBank Nucleotide #

NM_005862.2

NCBI Official Full Name

cohesin subunit SA-1

NCBI Official Synonym Full Names

stromal antigen 1

NCBI Official Symbol

STAG1

NCBI Official Synonym Symbols

SA1; SCC3A

UniProt Protein Name

Cohesin subunit SA-1

UniProt Synonym Protein Names

SCC3 homolog 1; Stromal antigen 1

Protein Family

Cofilin

UniProt Gene Name

STAG1

UniProt Synonym Gene Names

SA1

UniProt Entry Name

STAG1_HUMAN

NCBI Protein Information

cohesin subunit SA-1; SCC3 homolog 1; nuclear protein stromal antigen 1

UniProt Comments for STAG1

STAG1: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Belongs to the SCC3 family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: nucleoplasm; chromosome; nucleus; cytosol; chromatin; chromosome, pericentric region

Molecular Function: protein binding; chromatin binding

Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation

Research Articles on STAG1

1. Mutations in STAG1 is associated with acute myeloid leukemia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STAG1 antibody

Reference Product	PubMed Publications
STAG2 antibody	>8 publications with STAG1 and STAG2
RAD21 antibody	>6 publications with STAG1 and RAD21
SMC3 antibody	>6 publications with STAG1 and SMC3
SMC1A antibody	>2 publications with STAG1 and SMC1A
ESPL1 antibody	>1 publications with STAG1 and ESPL1

Pathways associated with anti-STAG1 antibody

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cohesin Loading Onto Chromatin Pathway antibodies	Cohesin Loading Onto Chromatin Pathway Diagram
Establishment Of Sister Chromatid Cohesion Pathway antibodies	Establishment Of Sister Chromatid Cohesion Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Meiosis Pathway antibodies	Meiosis Pathway Diagram
Meiotic Synapsis Pathway antibodies	Meiotic Synapsis Pathway Diagram
Mitotic Anaphase Pathway antibodies	Mitotic Anaphase Pathway Diagram

Diseases associated with anti-STAG1 antibody

Disease Name	Pubmed Publications
Prostatic Neoplasms Antibodies	>3 publications with STAG1 and Prostatic Neoplasms
Kidney Diseases Antibodies	>3 publications with STAG1 and Kidney Diseases
Anemia, Hemolytic Antibodies	>1 publications with STAG1 and Anemia, Hemolytic
Anemia Antibodies	>1 publications with STAG1 and Anemia
Hyperplasia Antibodies	>1 publications with STAG1 and Hyperplasia
Ovarian Neoplasms Antibodies	>1 publications with STAG1 and Ovarian Neoplasms
Lymphoma Antibodies	>1 publications with STAG1 and Lymphoma
Breast Neoplasms Antibodies	>1 publications with STAG1 and Breast Neoplasms
Pancreatic Neoplasms Antibodies	>1 publications with STAG1 and Pancreatic Neoplasms

Organs/Tissues associated with anti-STAG1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with STAG1 and Blood
Prostate Antibodies	>4 publications with STAG1 and Prostate
Bone Antibodies	>3 publications with STAG1 and Bone
Kidney Antibodies	>3 publications with STAG1 and Kidney
Connective Tissue Antibodies	>2 publications with STAG1 and Connective Tissue
Ovary Antibodies	>2 publications with STAG1 and Ovary
Nerve Antibodies	>2 publications with STAG1 and Nerve
Mouth Antibodies	>1 publications with STAG1 and Mouth
Thymus Antibodies	>1 publications with STAG1 and Thymus
Embryonic Tissue Antibodies	>1 publications with STAG1 and Embryonic Tissue