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TRA2B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6357814

TRA2B is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRA2B, Polyclonal Antibody
Full Product Name
TRA2B, ID (TRA2B, SFRS10, Transformer-2 protein homolog beta, Splicing factor, arginine/serine-rich 10, Transformer-2 protein homolog B) (APC)
Product Gene Name
anti-TRA2B antibody
Product Synonym Names
TRA2B; SFRS10; Transformer-2 protein homolog beta; Splicing factor; arginine/serine-rich 10; Transformer-2 protein homolog B
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
602719
3D Structure
ModBase 3D Structure for P62995
Immunogen
TRA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human TRA2B.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-TRA2B antibody

Antibodies; Splicing Factors
Applications Tested/Suitable for anti-TRA2B antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-TRA2B antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-TRA2B antibody

TRA2B Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TRA2B antibody detected the TRA2B protein (arrow).
Rabbit Anti-TRA2B Polyclonal Antibody – Cat# MBS6357814

Immunohistochemistry (IHC) of anti-TRA2B antibody

TRA2B Antibody (Center) (AP14688c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRA2B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-TRA2B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6357814

Product References and Citations for anti-TRA2B antibody

Benderska, N., et al. Biochim. Biophys. Acta 1799 (5-6), 448-453 (2010): Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009). Caporaso, N., et al. PLoS ONE 4 (2), E4653 (2009): Gabriel, B., et al. Acta Obstet Gynecol Scand 88(2):216-221(2009). Miele, A., et al. J. Cell. Biochem. 102(1):136-148(2007).

Other Notes

Small volumes of anti-TRA2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRA2B purchase

MBS6357814 is an antibody targeting TRA2B. Also known as TRA2B, ID (TRA2B, SFRS10, Transformer-2 protein homolog beta, Splicing factor, arginine/serine-rich 10, Transformer-2 protein homolog B) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRA2B. It may not necessarily be applicable to this product.

NCBI GI #
4759098
NCBI GeneID
6434
NCBI Accession #
NP_004584.1
UniProt Primary Accession #
P62995
UniProt Related Accession #
P62995
GenBank Nucleotide #
NP_004584.1
NCBI Official Full Name
transformer-2 protein homolog beta isoform 1
NCBI Official Synonym Full Names
transformer 2 beta homolog
NCBI Official Symbol
TRA2B
NCBI Official Synonym Symbols
SFRS10; SRFS10; TRAN2B; PPP1R156; TRA2-BETA; Htra2-beta
UniProt Protein Name
Transformer-2 protein homolog beta
UniProt Synonym Protein Names
Splicing factor, arginine/serine-rich 10; Transformer-2 protein homolog B
Protein Family
Transformer-2 protein
UniProt Gene Name
TRA2B
UniProt Synonym Gene Names
SFRS10; TRA-2 beta; TRA2-beta; hTRA2-beta
UniProt Entry Name
TRA2B_HUMAN
NCBI Protein Information
transformer-2 protein homolog beta

NCBI Summary for TRA2B

This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Research Articles on TRA2B

1. Findings demonstrate that Tra2b is upregulated in non-small cell lung cancer (NSCLC) and is associated with poor prognosis. Furthermore, Tra2b was identified as a direct target of miR-335. These results indicate that the interaction between miR-335 and Tra2b may play a vital role in the pathogenesis of NSCLC.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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