Rabbit Anti-UBE2Z Polyclonal Antibody – Cat# MBS6360858

UBE2Z Antibody – Rabbit Polyclonal

Name: UBE2Z Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6360858
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6360858

MBS6360858 is an antibody targeting UBE2Z. Also known as UBE2Z, CT (UBE2Z, Ubiquitin-conjugating enzyme E2 Z, Uba6-specific E2 conjugating enzyme 1, Ubiquitin carrier protein Z, Ubiquitin-protein ligase Z) (MaxLight 750). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UBE2Z, Polyclonal Antibody

Full Product Name

UBE2Z, CT (UBE2Z, Ubiquitin-conjugating enzyme E2 Z, Uba6-specific E2 conjugating enzyme 1, Ubiquitin carrier protein Z, Ubiquitin-protein ligase Z) (MaxLight 750)

Product Gene Name

anti-UBE2Z antibody

Product Synonym Names

UBE2Z; Ubiquitin-conjugating enzyme E2 Z; Uba6-specific E2 conjugating enzyme 1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human UBE2Z. Species Sequence Homology: mouse, rat and Xenopus

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

~30 kDa

Chromosome Location

Chromosome: 17; NC_000017.10 (46985731..47006422). Location: 17q21.32

OMIM

611362

3D Structure

ModBase 3D Structure for Q9H832

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 284-310 in the C-terminal region of human UBE2Z, UniProt Accession #NP_075567.2; Q9H832; Q6PCF7; Q3B7D1; Q3UE37.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-UBE2Z antibody

Antibodies; Ubiquitin Ligases

Applications Tested/Suitable for anti-UBE2Z antibody

FLISA, Western Blot (WB)

Application Notes for anti-UBE2Z antibody

WB: 1:1000
Applications are based on unconjugated antibody.

Product References and Citations for anti-UBE2Z antibody

1. Gu, X., et al. Mol. Biol. Rep. 34(3):183-188(2007). 2. Jin, J., et al. Nature 447(7148):1135-1138(2007).

Other Notes

Small volumes of anti-UBE2Z antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE2Z. It may not necessarily be applicable to this product.

NCBI GI #

302191680

NCBI GeneID

65264

NCBI Accession #

NP_075567.2

UniProt Primary Accession #

Q9H832

UniProt Secondary Accession #

Q6PCF7; Q3B7D1; Q3UE37

UniProt Related Accession #

Q9H832

GenBank Nucleotide #

NM_023079

NCBI Official Full Name

Homo sapiens ubiquitin-conjugating enzyme E2Z (UBE2Z), mRNA

NCBI Official Synonym Full Names

ubiquitin-conjugating enzyme E2Z

NCBI Official Symbol

UBE2Z

NCBI Official Synonym Symbols

USE1; HOYS7

UniProt Protein Name

Ubiquitin-conjugating enzyme E2 Z

UniProt Synonym Protein Names

Uba6-specific E2 conjugating enzyme 1; Use1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z

Protein Family

Ubiquitin-conjugating enzyme

UniProt Gene Name

UBE2Z

UniProt Synonym Gene Names

Use1

UniProt Entry Name

UBE2Z_HUMAN

NCBI Protein Information

ubiquitin-conjugating enzyme E2 Z; UBA6-specific enzyme E2; ubiquitin-protein ligase Z; ubiquitin carrier protein Z; uba6-specific E2 conjugating enzyme 1

NCBI Summary for UBE2Z

This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]

UniProt Comments for UBE2Z

Function: Catalyzes the covalent attachment of ubiquitin to other proteins

By similarity. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation. Ref.1 Ref.10

Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway: Protein modification; protein ubiquitination.

Subcellular location: Cytoplasm. Nucleus Ref.9.

Tissue specificity: Widely expressed. Highly in placenta, pancreas, spleen and testis. Ref.1 Ref.9

Sequence similarities: Belongs to the ubiquitin-conjugating enzyme family.

Sequence caution: The sequence AAH15890.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB14724.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on UBE2Z

1. UBE2Z was widely expressed in human tissues and is located on chromosome 17q21.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-UBE2Z antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies	Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies	Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Ubiquitin Mediated Proteolysis Pathway antibodies	Ubiquitin Mediated Proteolysis Pathway Diagram
Ubiquitin Mediated Proteolysis Pathway antibodies	Ubiquitin Mediated Proteolysis Pathway Diagram

Diseases associated with anti-UBE2Z antibody

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>1 publications with UBE2Z and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-UBE2Z antibody

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>1 publications with UBE2Z and Spleen
Stomach Antibodies	>1 publications with UBE2Z and Stomach
Pancreas Antibodies	>1 publications with UBE2Z and Pancreas
Placenta Antibodies	>1 publications with UBE2Z and Placenta
Testis Antibodies	>1 publications with UBE2Z and Testis