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anti-ALDH1A3 antibody :: Rabbit anti-Human, Mouse ALDH1A3 Polyclonal Antibody

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Catalog # MBS7047656
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

ALDH1A3, Polyclonal Antibody

Popular Item
Also Known As

ALDH1A3 Antibody

Product Synonym Names
Aldehyde dehydrogenase family 1 member A3; Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; ALDH1A3; ALDH6
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
512
OMIM
U07919 mRNA
3D Structure
ModBase 3D Structure for P47895
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Aldehyde dehydrogenase family 1 member A3 protein (2-210AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26712 / sc-26713
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ALDH1A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALDH1A3 antibody
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity).
Applications Tested/Suitable for anti-ALDH1A3 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ALDH1A3 antibody
WB: 1: 2000-1: 10000
IF: 1: 50-1: 200

Western Blot (WB) of anti-ALDH1A3 antibody
Western Blot
Positive WB detected in:U87 whole cell lysate,Mouse liver tissue
All lanes: ALDH1A3 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 57 kDa
Observed band size: 57 kDa

anti-ALDH1A3 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-ALDH1A3 antibody
Immunofluorescent analysis of PC3 cells using MBS7047656 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-ALDH1A3 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for ALDH1A3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,108 Da
NCBI Official Full Name
aldehyde dehydrogenase family 1 member A3 isoform 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member A3
NCBI Official Symbol
ALDH1A3  [Similar Products]
NCBI Official Synonym Symbols
ALDH6; MCOP8; RALDH3; ALDH1A6
  [Similar Products]
NCBI Protein Information
aldehyde dehydrogenase family 1 member A3
UniProt Protein Name
Aldehyde dehydrogenase family 1 member A3
UniProt Synonym Protein Names
Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3
UniProt Gene Name
ALDH1A3  [Similar Products]
UniProt Synonym Gene Names
ALDH6; RALDH-3; RalDH3  [Similar Products]
UniProt Entry Name
AL1A3_HUMAN
NCBI Summary for ALDH1A3
This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
UniProt Comments for ALDH1A3
ALDH1A3: Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system. Belongs to the aldehyde dehydrogenase family.

Protein type: Amino Acid Metabolism - histidine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.5; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 15q26.3

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; protein homodimerization activity; retinal dehydrogenase activity

Biological Process: embryonic eye morphogenesis; retinal metabolic process; retinoic acid metabolic process

Disease: Microphthalmia, Isolated 8
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-ALDH1A3 antibody
 Reference Product  PubMed Publications
 ADH7 antibody  >1 publications with ALDH1A3 and ADH7
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