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AURKC Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9403820

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
AURKC, Polyclonal Antibody
Full Product Name
AURKC Antibody
Product Gene Name
anti-AURKC antibody
Product Synonym Names
AIE2; AIK3; ARK3; AurC; SPGF5; STK13; aurora-C
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
0.5 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total AURKC protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
33,672 Da
OMIM
243060
3D Structure
ModBase 3D Structure for Q9UQB9
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the N terminal of human aurora kinase C
Target Name
AURKC

Product Categories/Family for anti-AURKC antibody

Total protein Ab
Applications Tested/Suitable for anti-AURKC antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-AURKC antibody
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50

Testing Data of anti-AURKC antibody

Gel: 10%SDS-PAGE Lysates (from left to right): Mouse testis tissue and hela cell, human liver cancer and A375 cell, 293T cell Amount of lysate: 40ug per lane Primary antibody: 1/150 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute
Rabbit Anti-AURKC Polyclonal Antibody – Cat# MBS9403820

Immunohistochemistry (IHC) of anti-AURKC antibody

Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/15.
Rabbit Anti-AURKC Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9403820

Other Notes

Small volumes of anti-AURKC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AURKC purchase

MBS9403820 is an antibody targeting AURKC. Also known as AURKC Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AURKC. It may not necessarily be applicable to this product.

NCBI GI #
62865639
NCBI GeneID
6795
NCBI Accession #
NP_001015878.1
UniProt Primary Accession #
Q9UQB9
UniProt Secondary Accession #
O60681; O75442; Q6AZY8; Q6DLZ0; Q9UPK5
UniProt Related Accession #
Q9UQB9
GenBank Nucleotide #
NM_001015878.1
NCBI Official Full Name
aurora kinase C isoform 1
NCBI Official Synonym Full Names
aurora kinase C
NCBI Official Symbol
AURKC
NCBI Official Synonym Symbols
AIE2; AIK3; ARK3; AurC; SPGF5; STK13; HEL-S-90; aurora-C
UniProt Protein Name
Aurora kinase C
UniProt Synonym Protein Names
Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 2; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C
Protein Family
Aurora kinase
UniProt Gene Name
AURKC
UniProt Synonym Gene Names
AIE2; AIK3; AIRK3; ARK3; STK13; ARK-3; Aurora-related kinase 3
UniProt Entry Name
AURKC_HUMAN
NCBI Protein Information
aurora kinase C

UniProt Comments for AURKC

AurC: a member of the AUR family of kinases. May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. Localized to centrosome from anaphase to cytokinesis. Two splice-variant isoforms have been described.

Protein type: Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Other group; AUR family

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: spindle microtubule; cytoplasm; spindle; condensed chromosome; spindle pole centrosome; midbody; spindle midzone; condensed nuclear chromosome, pericentric region

Molecular Function: protein serine/threonine/tyrosine kinase activity; histone serine kinase activity; ATP binding; protein kinase activity

Biological Process: positive regulation of cytokinesis; meiotic cell cycle; spindle midzone assembly involved in mitosis; histone modification; regulation of signal transduction; cytokinesis; attachment of spindle microtubules to kinetochore; protein amino acid phosphorylation

Disease: Spermatogenic Failure 5
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Research Articles on AURKC

1. may play an important role in the development of colorectal cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AURKC antibody

 Reference Product  PubMed Publications
 AURKB antibody  >48 publications with AURKC and AURKB
 INCENP antibody  >11 publications with AURKC and INCENP
 BUB1B antibody  >3 publications with AURKC and BUB1B
 BIRC5 antibody  >3 publications with AURKC and BIRC5
 CDCA8 antibody  >2 publications with AURKC and CDCA8
 TACC1 antibody  >1 publications with AURKC and TACC1

Pathways associated with anti-AURKC antibody

 Products by Pathway  Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Aurora C Signaling Pathway antibodies  Aurora C Signaling Pathway Diagram
 Signaling By Aurora Kinases Pathway antibodies  Signaling By Aurora Kinases Pathway Diagram

Diseases associated with anti-AURKC antibody

 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >14 publications with AURKC and Infertility, Male
 Cell Transformation, Neoplastic Antibodies  >8 publications with AURKC and Cell Transformation, Neoplastic
 Abnormalities, Multiple Antibodies  >3 publications with AURKC and Abnormalities, Multiple
 Infertility, Female Antibodies  >3 publications with AURKC and Infertility, Female
 Necrosis Antibodies  >2 publications with AURKC and Necrosis
 Neoplasms, Experimental Antibodies  >2 publications with AURKC and Neoplasms, Experimental
 Intestinal Neoplasms Antibodies  >1 publications with AURKC and Intestinal Neoplasms
 Kidney Diseases Antibodies  >1 publications with AURKC and Kidney Diseases
 Weight Loss Antibodies  >1 publications with AURKC and Weight Loss
 Inflammation Antibodies  >1 publications with AURKC and Inflammation

Organs/Tissues associated with anti-AURKC antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >13 publications with AURKC and Testis
 Kidney Antibodies  >3 publications with AURKC and Kidney
 Brain Antibodies  >1 publications with AURKC and Brain
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