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DIRC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9603966

Description: Electrogenic metabolite transporter.Post-translational Modifications: Cleaved in lysosomes by cathepsin L between Leu-214 and Ala-261, generating a N-glycosylated N-terminal and a non-glycosylated C-terminal fragment.Similarity: Belongs to the… More details

$325 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DIRC2, Polyclonal Antibody
Full Product Name
DIRC2 Antibody
Product Gene Name
Product Synonym Names
DIRC 2; dirc2; DIRC2_HUMAN; Disrupted in renal cancer protein 2; Disrupted in renal carcinoma 2; Disrupted in renal carcinoma protein 2; FLJ14784; NP_116228; RCC 4; RCC4; Renal cell carcinoma 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Concentration
1mg/ml (lot specific)
Specificity
DIRC2 antibody detects endogenous levels of total DIRC2
Antibody/Peptide Pairs
DIRC2 peptide (MBS9622683) is used for blocking the activity of DIRC2 antibody (MBS9603966)
Molecular Weight
Observed: 52 kDa
Predicted: 53 kDa
3D Structure
ModBase 3D Structure for Q96SL1
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide
Subcellular Location
Lysosome membrane.
Tissue Specificity
Ubiquitous. Expressed in proximal tubular cells of the kidney.
Predicted Cross Reactivity
Pig, Horse, Sheep, Rabbit, Xenopus
Similarity
Pig (91%), Horse (91%), Sheep (82%), Rabbit (91%), Xenopus (100%)
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DIRC2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-DIRC2 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-DIRC2 antibody

Western blot analysis of DIRC2 expression in MCF7 Cell Lysate, The lane on the left is treated with the antigen-specific peptide.
Rabbit Anti-DIRC2 Polyclonal Antibody – Cat# MBS9603966

Other Notes

Small volumes of anti-DIRC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DIRC2 purchase

MBS9603966 is an antibody targeting DIRC2. Also known as DIRC2 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DIRC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
disrupted in renal carcinoma protein 2
NCBI Official Synonym Full Names
solute carrier family 49 member 4
NCBI Official Symbol
SLC49A4
NCBI Official Synonym Symbols
RCC4; DIRC2
UniProt Protein Name
Disrupted in renal carcinoma protein 2
UniProt Synonym Protein Names
Disrupted in renal cancer protein 2
UniProt Gene Name
DIRC2
NCBI Protein Information
disrupted in renal carcinoma protein 2

NCBI Summary for DIRC2

This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for DIRC2

Electrogenic metabolite transporter.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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