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FRK Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8573441

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. More details

$380 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FRK, Polyclonal Antibody
Full Product Name
FRK Polyclonal Antibody
Product Gene Name
anti-FRK antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
41kDa; 58kDa
OMIM
606573
3D Structure
ModBase 3D Structure for P42685
Immunogen
Recombinant protein of human FRK (NP_002022.1).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FRK antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-FRK antibody
WB: 1:500-1:2000
IF: 1:50-1:200

Other Notes

Small volumes of anti-FRK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FRK purchase

MBS8573441 is an antibody targeting FRK. Also known as FRK Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FRK. It may not necessarily be applicable to this product.

NCBI GI #
4503787
NCBI GeneID
2444
NCBI Accession #
NP_002022.1
UniProt Primary Accession #
P42685
UniProt Related Accession #
P42685
GenBank Nucleotide #
NP_002022.1
NCBI Official Full Name
tyrosine-protein kinase FRK
NCBI Official Synonym Full Names
fyn related Src family tyrosine kinase
NCBI Official Symbol
FRK
NCBI Official Synonym Symbols
GTK; RAK; PTK5
UniProt Protein Name
Tyrosine-protein kinase FRK
UniProt Synonym Protein Names
FYN-related kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5
Protein Family
Tyrosine-protein kinase
UniProt Gene Name
FRK
UniProt Synonym Gene Names
PTK5; RAK
UniProt Entry Name
FRK_HUMAN
NCBI Protein Information
tyrosine-protein kinase FRK

UniProt Comments for FRK

FRK: a tyrosine kinase of the Src family. Expressed in cell lines derived from tissues of lymphoid, brain, breast, colon and bladder origin. A nuclear protein that may function during G1 and S phase of the cell cycle to suppress growth.

Protein type: Protein kinase, TK; EC 2.7.10.2; Tumor suppressor; Kinase, protein; Protein kinase, tyrosine (non-receptor); TK group; Src family

Chromosomal Location of Human Ortholog: 6q21-q22.3

Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm; intracellular; nucleus

Molecular Function: protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding

Biological Process: negative regulation of cell proliferation; cell migration; innate immune response; cell differentiation; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation
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Research Articles on FRK

1. Targetable fusions of the FRK tyrosine kinase in ALK-negative anaplastic large cell lymphoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-FRK antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >43 publications with FRK and Neoplasms
 Ovarian Neoplasms Antibodies  >8 publications with FRK and Ovarian Neoplasms
 Nervous System Diseases Antibodies  >7 publications with FRK and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with FRK and Brain Diseases
 Neoplasm Invasiveness Antibodies  >6 publications with FRK and Neoplasm Invasiveness
 Drug Toxicity Antibodies  >4 publications with FRK and Drug Toxicity
 Neoplasms, Experimental Antibodies  >4 publications with FRK and Neoplasms, Experimental
 Necrosis Antibodies  >4 publications with FRK and Necrosis
 Lung Neoplasms Antibodies  >3 publications with FRK and Lung Neoplasms
 Inflammation Antibodies  >2 publications with FRK and Inflammation

Organs/Tissues associated with anti-FRK antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >7 publications with FRK and Liver
 Pancreas Antibodies  >5 publications with FRK and Pancreas
 Prostate Antibodies  >5 publications with FRK and Prostate
 Placenta Antibodies  >3 publications with FRK and Placenta
 Mammary Gland Antibodies  >3 publications with FRK and Mammary Gland
 Connective Tissue Antibodies  >2 publications with FRK and Connective Tissue
 Ascites Antibodies  >1 publications with FRK and Ascites
 Bladder Antibodies  >1 publications with FRK and Bladder
 Testis Antibodies  >1 publications with FRK and Testis
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