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HSD17B2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9240446

Rabbit polyclonal antibody to HSD17B2KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HSD17B2. The exact sequence is proprietary. More details

$265 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HSD17B2, Polyclonal Antibody
Full Product Name
Anti-HSD17B2 Antibody
Product Gene Name
anti-HSD17B2 antibody
Product Synonym Names
EDH17B2; Estradiol 17-beta-dehydrogenase 2; 17-beta-hydroxysteroid dehydrogenase type 2; 17-beta-HSD 2; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Microsomal 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
42,785 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (82068858..82132139). Location: 16q24.1-q24.2
OMIM
109685
3D Structure
ModBase 3D Structure for P37059
Applications Tested/Suitable for anti-HSD17B2 antibody
Western Blot (WB)

Wester Blot (WB) of anti-HSD17B2 antibody

Dilution: WB (1/500 - 1/1000)
Western blot analysis of HSD17B2 expression in HCT116 (A), CT26 (B) whole cell lysates.
Rabbit Anti-HSD17B2 Polyclonal Antibody – Cat# MBS9240446

Other Notes

Small volumes of anti-HSD17B2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSD17B2 purchase

MBS9240446 is an antibody targeting HSD17B2. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSD17B2. It may not necessarily be applicable to this product.

NCBI GI #
4504503
NCBI GeneID
3294
NCBI Accession #
NP_002144.1
UniProt Primary Accession #
P37059
UniProt Secondary Accession #
B2R7T4
UniProt Related Accession #
P37059
GenBank Nucleotide #
NM_002153.2
NCBI Official Full Name
estradiol 17-beta-dehydrogenase 2
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 2
NCBI Official Symbol
HSD17B2
NCBI Official Synonym Symbols
HSD17; SDR9C2; EDH17B2
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 2
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase type 2; 17-beta-HSD 2; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Microsomal 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase
Protein Family
Estradiol 17 beta-dehydrogenase
UniProt Gene Name
HSD17B2
UniProt Synonym Gene Names
EDH17B2; 17-beta-HSD 2
UniProt Entry Name
DHB2_HUMAN
NCBI Protein Information
estradiol 17-beta-dehydrogenase 2; E2DH; 20-alpha-HSD; 17-beta-HSD 2; testosterone 17-beta-dehydrogenase; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 2; microsomal 17-beta-hydroxysteroid dehydrogenase; short chain dehy

UniProt Comments for HSD17B2

HSD17B2: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.62; EC 1.1.1.239; Lipid Metabolism - androgen and estrogen; Endoplasmic reticulum; Membrane protein, integral; Oxidoreductase

Chromosomal Location of Human Ortholog: 16q24.1-q24.2

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: estradiol 17-beta-dehydrogenase activity; 20-alpha-hydroxysteroid dehydrogenase activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity

Biological Process: response to retinoic acid; in utero embryonic development; steroid biosynthetic process; placenta development
Show more

Research Articles on HSD17B2

1. no significant difference in the genotype and allele frequencies of rs8191246 between uterine leiomyoma cases and controls

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-HSD17B2 antibody

 Products by Pathway  Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram

Diseases associated with anti-HSD17B2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >395 publications with HSD17B2 and Neoplasms
 Breast Neoplasms Antibodies  >220 publications with HSD17B2 and Breast Neoplasms
 Adenocarcinoma Antibodies  >67 publications with HSD17B2 and Adenocarcinoma
 Urogenital Abnormalities Antibodies  >48 publications with HSD17B2 and Urogenital Abnormalities
 Endometriosis Antibodies  >47 publications with HSD17B2 and Endometriosis
 Drug Toxicity Antibodies  >42 publications with HSD17B2 and Drug Toxicity
 Hyperplasia Antibodies  >40 publications with HSD17B2 and Hyperplasia
 Ovarian Neoplasms Antibodies  >38 publications with HSD17B2 and Ovarian Neoplasms
 Neoplasms, Experimental Antibodies  >38 publications with HSD17B2 and Neoplasms, Experimental
 Prostatic Neoplasms Antibodies  >26 publications with HSD17B2 and Prostatic Neoplasms

Organs/Tissues associated with anti-HSD17B2 antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >351 publications with HSD17B2 and Ovary
 Placenta Antibodies  >292 publications with HSD17B2 and Placenta
 Liver Antibodies  >167 publications with HSD17B2 and Liver
 Brain Antibodies  >97 publications with HSD17B2 and Brain
 Kidney Antibodies  >73 publications with HSD17B2 and Kidney
 Prostate Antibodies  >69 publications with HSD17B2 and Prostate
 Muscle Antibodies  >49 publications with HSD17B2 and Muscle
 Bone Antibodies  >28 publications with HSD17B2 and Bone
 Adipose Tissue Antibodies  >24 publications with HSD17B2 and Adipose Tissue
 Lung Antibodies  >23 publications with HSD17B2 and Lung
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