• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

OCRL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9508972

MBS9508972 is an antibody targeting OCRL. Also known as OCRL Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$300 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
OCRL, Polyclonal Antibody
Full Product Name
OCRL Antibody
Product Gene Name
Product Synonym Names
Inositol polyphosphate 5-phosphatase OCRL-1; Lowe oculocerebrorenal syndrome protein; OCRL; INPP5F; OCRL1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
1 mg/ml (lot specific)
Specificity
OCRL antibody detects endogenous levels of OCRL.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Molecular Weight
104 kDa
OMIM
M88162 mRNA
3D Structure
ModBase 3D Structure for Q01968
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human OCRL.
Immunogen Range
150-199
Applications Tested/Suitable for anti-OCRL antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-OCRL antibody
WB: 1:500~1:1000
ELISA: 1:10000

Western Blot (WB) of anti-OCRL antibody

Western blot analysis of lysate from COLO205 cells treated with Forskolin, using OCRL antibody.
Rabbit Anti-OCRL Polyclonal Antibody – Cat# MBS9508972

Other Notes

Small volumes of anti-OCRL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OCRL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inositol polyphosphate 5-phosphatase OCRL-1 isoform a
NCBI Official Synonym Full Names
OCRL, inositol polyphosphate-5-phosphatase
NCBI Official Symbol
OCRL
NCBI Official Synonym Symbols
LOCR; NPHL2; OCRL1; INPP5F; OCRL-1
UniProt Protein Name
Inositol polyphosphate 5-phosphatase OCRL-1
UniProt Synonym Protein Names
Lowe oculocerebrorenal syndrome protein
UniProt Gene Name
OCRL
UniProt Synonym Gene Names
INPP5F; OCRL1
NCBI Protein Information
inositol polyphosphate 5-phosphatase OCRL-1

NCBI Summary for OCRL

This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Show more

UniProt Comments for OCRL

Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976).
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000