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SEPT6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645391

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SEPT6, Polyclonal Antibody
Full Product Name
SEPT6, CT (SEPT6, KIAA0128, SEP2, Septin-6)
Product Gene Name
Product Synonym Names
Anti -SEPT6, CT (SEPT6, KIAA0128, SEP2, Septin-6)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
49,717 Da
Chromosome Location
Chromosome: X; NC_000023.10 (118749687..118827333, complement). Location: Xq24
OMIM
300683
3D Structure
ModBase 3D Structure for Q14141
Immunogen
SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-426 amino acids from the C-terminal region of human SEPT6.
Applications Tested/Suitable for anti-SEPT6 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SEPT6 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-SEPT6 antibody

SEPT6 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SEPT6 antibody detected the SEPT6 protein (arrow).
Rabbit Anti-SEPT6 Polyclonal Antibody – Cat# MBS645391

Western Blot (WB) of anti-SEPT6 antibody

SEPT6 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SEPT6 antibody detected the SEPT6 protein (arrow).
Rabbit Anti-SEPT6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS645391

Other Notes

Small volumes of anti-SEPT6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEPT6 purchase

MBS645391 is an antibody targeting SEPT6. Also known as SEPT6, CT (SEPT6, KIAA0128, SEP2, Septin-6). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEPT6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
septin-6 isoform D
NCBI Official Synonym Full Names
septin 6
NCBI Official Symbol
SEPT6
NCBI Official Synonym Symbols
SEP2; SEPT2; RP5-876A24.2
UniProt Protein Name
Septin-6
UniProt Gene Name
SEPT6
UniProt Synonym Gene Names
KIAA0128; SEP2
UniProt Entry Name
SEPT6_HUMAN
NCBI Protein Information
septin-6; septin 2

UniProt Comments for SEPT6

SEPT6: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Belongs to the septin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Cytoskeletal

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: synaptic vesicle; spindle; nerve terminal; midbody; cleavage furrow

Molecular Function: protein binding; GTP binding

Biological Process: viral reproduction; cytokinesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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