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UST Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9209776

Uronyl 2-sulfotransferase transfers sulfate to the2-position of uronyl residues, such as iduronyl residues indermatan sulfate and glucuronyl residues in chondroitin sulfate(Kobayashi et al., 1999 [PubMed 10187838]). More details

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Product Overview

Online Datasheet in PDF
Product Name
UST, Polyclonal Antibody
Full Product Name
UST Antibody (C-term)
Product Gene Name
Product Synonym Names
Uronyl 2-sulfotransferase; 282-; UST; DS2ST
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human (Predicted Reactivity: Mouse)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.46 (lot specific)
Specificity
This UST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human UST.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
UST peptide (MBS9222434) is used for blocking the activity of UST antibody (MBS9209776)
Molecular Weight
47673
Immunogen Sequence Positions
291-319
OMIM
610752
3D Structure
ModBase 3D Structure for Q9Y2C2
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN

Product Categories/Family for anti-UST antibody

Applications Tested/Suitable for anti-UST antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-UST antibody
WB~~1:1000

Western Blot (WB) of anti-UST antibody

UST Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UST antibody detected the UST protein (arrow).
Rabbit Anti-UST Polyclonal Antibody – Cat# MBS9209776

Product References and Citations for anti-UST antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Uher, R., et al. Am J Psychiatry 167(5):555-564(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Xu, D., et al. J. Biol. Chem. 282(11):8356-8367(2007)
Ohtake, S., et al. J. Biol. Chem. 280(47):39115-39123(2005)

Other Notes

Small volumes of anti-UST antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UST purchase

MBS9209776 is an antibody targeting UST. Also known as UST Antibody (C-term). Reactive in Human (Predicted Reactivity: Mouse). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UST. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uronyl 2-sulfotransferase
NCBI Official Synonym Full Names
uronyl-2-sulfotransferase
NCBI Official Symbol
UST
NCBI Official Synonym Symbols
2OST
UniProt Protein Name
Uronyl 2-sulfotransferase
UniProt Gene Name
UST
UniProt Synonym Gene Names
DS2ST
UniProt Entry Name
UST_HUMAN
NCBI Protein Information
uronyl 2-sulfotransferase

NCBI Summary for UST

Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]

UniProt Comments for UST

UST: Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin. Belongs to the sulfotransferase 3 family.

Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.8.2.-; Transferase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q25.1

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: sulfotransferase activity

Biological Process: chondroitin sulfate metabolic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; protein amino acid sulfation; pathogenesis; dermatan sulfate biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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