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ALDH3B1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2520409

The aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular gene spans about 20 kb of genomic DNA and is composed of 9 coding exons.… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ALDH3B1, Polyclonal Antibody
Full Product Name
ALDH3B1 Polyclonal Antibody
Product Gene Name
anti-ALDH3B1 antibody
Product Synonym Names
ALDH4; ALDH7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
47,683 Da
OMIM
600466
Immunogen
Recombinant protein of human ALDH3B1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ALDH3B1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ALDH3B1 antibody
WB: 1:200-1:1000
IHC: 1:25-1:100

Western Blot (WB) of anti-ALDH3B1 antibody

Western Blot analysis of Human normal kidney and liver tissue, Human liver cancer tissue using ALDH3B1 Polyclonal Antibody at dilution of 1:300
Rabbit Anti-ALDH3B1 Polyclonal Antibody – Cat# MBS2520409

Immunohistochemistry (IHC) of anti-ALDH3B1 antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer using ALDH3B1 Polyclonal Antibody at dilution of 1:30
Rabbit Anti-ALDH3B1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2520409

Other Notes

Small volumes of anti-ALDH3B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH3B1 purchase

MBS2520409 is an antibody targeting ALDH3B1. Also known as ALDH3B1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH3B1. It may not necessarily be applicable to this product.

NCBI GI #
586946394
NCBI GeneID
221
NCBI Accession #
NP_001276988.1
UniProt Secondary Accession #
Q53XL5; Q8N515; Q96CK8; A3FMP9
UniProt Related Accession #
P43353
GenBank Nucleotide #
NM_001290059.1
NCBI Official Full Name
aldehyde dehydrogenase family 3 member B1 isoform d
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family, member B1
NCBI Official Symbol
ALDH3B1
NCBI Official Synonym Symbols
ALDH4; ALDH7
UniProt Protein Name
Aldehyde dehydrogenase family 3 member B1
UniProt Synonym Protein Names
Aldehyde dehydrogenase 7
Protein Family
Aldehyde dehydrogenase family
UniProt Gene Name
ALDH3B1
UniProt Synonym Gene Names
ALDH7
UniProt Entry Name
AL3B1_HUMAN
NCBI Protein Information
aldehyde dehydrogenase family 3 member B1; aldehyde dehydrogenase 3B1; aldehyde dehydrogenase 7

NCBI Summary for ALDH3B1

This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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UniProt Comments for ALDH3B1

ALDH3B1: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.2.1.5; Amino Acid Metabolism - histidine; Oxidoreductase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tyrosine

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytoplasm; plasma membrane; cytosol; vesicle

Molecular Function: aldehyde dehydrogenase [NAD(P)+] activity; 3-chloroallyl aldehyde dehydrogenase activity

Biological Process: aldehyde catabolic process; ethanol catabolic process; alcohol metabolic process; lipid metabolic process
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Research Articles on ALDH3B1

1. the likely physiological function of ALDH3B1 is to oxidize lipid-derived aldehydes generated in the plasma membrane and not to be involved in the sphingolipid metabolism in the endoplasmic reticulum.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH3B1 antibody

 Reference Product  PubMed Publications
 COMT antibody  >3 publications with ALDH3B1 and COMT
 ACSS2 antibody  >1 publications with ALDH3B1 and ACSS2

Pathways associated with anti-ALDH3B1 antibody

 Products by Pathway  Pathway Diagram
 2'-deoxy-alpha-D-ribose 1-phosphate Degradation Pathway antibodies  2'-deoxy-alpha-D-ribose 1-phosphate Degradation Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram

Diseases associated with anti-ALDH3B1 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with ALDH3B1 and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with ALDH3B1 and Liver Diseases
 Ovarian Neoplasms Antibodies  >1 publications with ALDH3B1 and Ovarian Neoplasms
 Fatty Liver, Alcoholic Antibodies  >1 publications with ALDH3B1 and Fatty Liver, Alcoholic
 Lung Neoplasms Antibodies  >1 publications with ALDH3B1 and Lung Neoplasms
 Ovarian Diseases Antibodies  >1 publications with ALDH3B1 and Ovarian Diseases
 Kidney Diseases Antibodies  >1 publications with ALDH3B1 and Kidney Diseases
 Fatty Liver Antibodies  >1 publications with ALDH3B1 and Fatty Liver

Organs/Tissues associated with anti-ALDH3B1 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with ALDH3B1 and Testis
 Eye Antibodies  >2 publications with ALDH3B1 and Eye
 Kidney Antibodies  >2 publications with ALDH3B1 and Kidney
 Lung Antibodies  >2 publications with ALDH3B1 and Lung
 Pancreas Antibodies  >1 publications with ALDH3B1 and Pancreas
 Brain Antibodies  >1 publications with ALDH3B1 and Brain
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