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RDX Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2522771

Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RDX, Polyclonal Antibody
Full Product Name
RDX Polyclonal Antibody
Product Gene Name
Product Synonym Names
DFNB24
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.7mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
71,049 Da
OMIM
179410
Immunogen
Recombinant protein of human RDX
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RDX antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RDX antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-RDX antibody

Western Blot analysis of Hela cell, Human fetal brain and hepatocellular carcinoma tissue using RDX Polyclonal Antibody at dilution of 1:700
Rabbit Anti-RDX Polyclonal Antibody – Cat# MBS2522771

Immunohistochemistry (IHC) of anti-RDX antibody

Immunohistochemistry of paraffin-embedded Human cervical cancer using RDX Polyclonal Antibody at dilution of 1:60
Rabbit Anti-RDX Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2522771

Immunohistochemistry (IHC) of anti-RDX antibody

Immunohistochemistry of paraffin-embedded Human brain using RDX Polyclonal Antibody at dilution of 1:60
Rabbit Anti-RDX Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2522771

Other Notes

Small volumes of anti-RDX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RDX purchase

MBS2522771 is an antibody targeting RDX. Also known as RDX Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RDX. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
RDX protein, partial
NCBI Official Synonym Full Names
radixin
NCBI Official Symbol
RDX
NCBI Official Synonym Symbols
DFNB24
UniProt Protein Name
Radixin
Protein Family
UniProt Gene Name
RDX
UniProt Entry Name
RADI_HUMAN
NCBI Protein Information
radixin

NCBI Summary for RDX

Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
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UniProt Comments for RDX

Radixin: a cytoskeletal protein of the ERM family which includes ezrin and moiesin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. May play a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: extracellular space; focal adhesion; T-tubule; ruffle; stereocilium; cytoskeleton; extrinsic to membrane; apical part of cell; lamellipodium; cytoplasm; plasma membrane; cleavage furrow; filopodium

Molecular Function: protein binding; actin binding

Biological Process: microvillus biogenesis; apical protein localization; actin filament capping

Disease: Deafness, Autosomal Recessive 24
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RDX antibody

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