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TICAM1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9133638
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This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TICAM1, Polyclonal Antibody
Full Product Name
TICAM1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
Immunogen Sequence
QDKLLYLKHK LKTPRPGCQG QDLLHAMVLL KLGQETEARI SLEALKADAV ARLVARQWAG VDSTEDPEEP PDVSWAVARL YHLLAEEKLC PASLRDVAYQ EAVRTLSSRD DHRLGELQDE ARNRCGWDIA GDPGSIRTLQ SNLGCLPPSS ALPSGTRSLP RPIDGVSDWS QGCSLRSTGS P
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
76kDa
OMIM
AB093555 mRNA
3D Structure
ModBase 3D Structure for Q8IUC6
Immunogen
Recombinant protein of human TICAM1
Immunogen Species
Human
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Cytoplasmic vesicle, autophagosome

Product Categories/Family for anti-TICAM1 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TICAM1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TICAM1 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Immunohistochemistry (IHC) of anti-TICAM1 antibody

Immunohistochemistry of paraffin-embedded rat lung using TICAM1 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TICAM1 Polyclonal Antibody – Cat# MBS9133638

Immunohistochemistry (IHC) of anti-TICAM1 antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using TICAM1 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TICAM1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9133638

Immunohistochemistry (IHC) of anti-TICAM1 antibody

Immunohistochemistry of paraffin-embedded mouse lung using TICAM1 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TICAM1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9133638

Other Notes

Small volumes of anti-TICAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TICAM1 purchase

MBS9133638 is an antibody targeting TICAM1. Also known as TICAM1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TICAM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TIR domain-containing adapter molecule 1
NCBI Official Synonym Full Names
toll like receptor adaptor molecule 1
NCBI Official Symbol
TICAM1
NCBI Official Synonym Symbols
TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1
UniProt Protein Name
TIR domain-containing adapter molecule 1
UniProt Synonym Protein Names
Proline-rich, vinculin and TIR domain-containing protein B; Putative NF-kappa-B-activating protein 502H; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; MyD88-3; TIR domain-containing adapter protein inducing IFN-beta
UniProt Gene Name
TICAM1
UniProt Synonym Gene Names
PRVTIRB; TRIF; TICAM-1; MyD88-3; TIR domain-containing adapter protein inducing IFN-beta
NCBI Protein Information
TIR domain-containing adapter molecule 1

UniProt Comments for TICAM1

Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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