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GLP1R Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7048280

This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glp1r, Polyclonal Antibody
Full Product Name
Glp1r Antibody, Biotin conjugated
Product Gene Name
anti-Glp1r antibody
Product Synonym Names
Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Glp1r
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: Glp1r (MBS7048277)
Biotin Conjugated Antibody: Glp1r (MBS7048280)
Molecular Weight
53,028 Da
3D Structure
ModBase 3D Structure for O35659
Immunogen
Recombinant Mouse Glucagon-like peptide 1 receptor protein (24-145AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Biotin
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-Glp1r antibody
ELISA (EIA)

Other Notes

Small volumes of anti-Glp1r antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Glp1r purchase

MBS7048280 is an antibody targeting Glp1r. Also known as Glp1r Antibody, Biotin conjugated. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Glp1r. It may not necessarily be applicable to this product.

NCBI GI #
111378379
NCBI GeneID
14652
NCBI Accession #
NP_067307.2
UniProt Primary Accession #
O35659
UniProt Secondary Accession #
Q1JQR8
UniProt Related Accession #
O35659
GenBank Nucleotide #
NM_021332.2
NCBI Official Full Name
glucagon-like peptide 1 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 1 receptor
NCBI Official Symbol
Glp1r
NCBI Official Synonym Symbols
GLP-1R; GLP1Rc
UniProt Protein Name
Glucagon-like peptide 1 receptor
Protein Family
Glucagon-like peptide 1 receptor
UniProt Gene Name
Glp1r
UniProt Synonym Gene Names
GLP-1 receptor; GLP-1-R; GLP-1R
UniProt Entry Name
GLP1R_MOUSE
NCBI Protein Information
glucagon-like peptide 1 receptor

UniProt Comments for Glp1r

GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: integral to plasma membrane

Molecular Function: peptide hormone binding; peptide receptor activity; peptide receptor activity, G-protein coupled; receptor activity

Biological Process: associative learning; cAMP-mediated signaling; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; hormone secretion; insulin secretion; learning and/or memory; memory; negative regulation of apoptosis; negative regulation of neuron apoptosis; neuropeptide signaling pathway; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of heart contraction; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; regulation of calcium ion transport; regulation of heart contraction; release of sequestered calcium ion into cytosol; response to glucose stimulus; response to stress
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Research Articles on Glp1r

1. CB1 activation negatively impacts GLP-1R-mediated insulin secretion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Glp1r antibody

 Reference Product  PubMed Publications
 Gip antibody  >104 publications with Glp1r and Gip
 Pomc antibody  >14 publications with Glp1r and Pomc
 Vip antibody  >12 publications with Glp1r and Vip
 Gcg antibody  >12 publications with Glp1r and Gcg
 Iapp antibody  >6 publications with Glp1r and Iapp
 Mc4r antibody  >5 publications with Glp1r and Mc4r
 Pth antibody  >3 publications with Glp1r and Pth
 Crh antibody  >3 publications with Glp1r and Crh
 Adcy8 antibody  >1 publications with Glp1r and Adcy8

Pathways associated with anti-Glp1r antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway antibodies  Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-Glp1r antibody

 Disease Name  Pubmed Publications
 Weight Loss Antibodies  >179 publications with Glp1r and Weight Loss
 Hyperglycemia Antibodies  >154 publications with Glp1r and Hyperglycemia
 Hypoglycemia Antibodies  >145 publications with Glp1r and Hypoglycemia
 Disease Models, Animal Antibodies  >128 publications with Glp1r and Disease Models, Animal
 Insulin Resistance Antibodies  >121 publications with Glp1r and Insulin Resistance
 Weight Gain Antibodies  >82 publications with Glp1r and Weight Gain
 Vascular Diseases Antibodies  >82 publications with Glp1r and Vascular Diseases
 Inflammation Antibodies  >54 publications with Glp1r and Inflammation
 Heart Diseases Antibodies  >46 publications with Glp1r and Heart Diseases
 Brain Diseases Antibodies  >43 publications with Glp1r and Brain Diseases

Organs/Tissues associated with anti-Glp1r antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >15 publications with Glp1r and Mixed
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