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VANGL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6362232

Planar cell polarity (PCP) is the term given to global cell polarization, such as the alignment of mammalian body hair along the anterior-posterior axis or the orientation of steriocilia bundles in the inner ear. VANGL2 is a PCP protein that is involved in… More details

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Product Overview

Online Datasheet in PDF
Product Name
VANGL2, Polyclonal Antibody
Full Product Name
VANGL2, NT (VANGL2, KIAA1215, STB1, Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2) (MaxLight 650)
Product Gene Name
Product Synonym Names
VANGL2; KIAA1215; STB1; Vang-like protein 2; Loop-tail protein 1 homolog; Strabismus 1; Van Gogh-like protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
600533
3D Structure
ModBase 3D Structure for Q9ULK5
Immunogen
VANGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human VANGL2.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-VANGL2 antibody

Applications Tested/Suitable for anti-VANGL2 antibody
Western Blot (WB), FLISA
Application Notes for anti-VANGL2 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-VANGL2 antibody

Lei, Y.P., et al. N. Engl. J. Med. 362(23):2232-2235(2010). Yates, L.L., et al. Hum. Mol. Genet. 19(11):2251-2267(2010). Cantrell, V.A., et al. Cancer Lett. 287(1):54-61(2010). Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009). Devenport, D., et al. Nat. Cell Biol. 10(11):1257-1268(2008).

Other Notes

Small volumes of anti-VANGL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VANGL2 purchase

MBS6362232 is an antibody targeting VANGL2. Also known as VANGL2, NT (VANGL2, KIAA1215, STB1, Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2) (MaxLight 650). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VANGL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
vang-like protein 2
NCBI Official Synonym Full Names
VANGL planar cell polarity protein 2
NCBI Official Symbol
VANGL2
NCBI Official Synonym Symbols
LPP1; LTAP; STB1; STBM; STBM1
UniProt Protein Name
Vang-like protein 2
UniProt Synonym Protein Names
Loop-tail protein 1 homolog; Strabismus 1; Van Gogh-like protein 2
Protein Family
UniProt Gene Name
VANGL2
UniProt Synonym Gene Names
KIAA1215; STB1
UniProt Entry Name
VANG2_HUMAN
NCBI Protein Information
vang-like protein 2

NCBI Summary for VANGL2

The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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