Human FURIN Recombinant Protein – Cat# MBS189167

Figure 1. Human FURIN Protein, His Tag on SDS-PAGE under reducing condition.

FURIN Human Recombinant Protein

Name: FURIN Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS189167
Price: 340 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS189167

Recombinant human FURIN protein with C-terminal 6×His tagThis gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive… More details

$340 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FURIN, Recombinant Protein

Full Product Name

Human FURIN Protein, His Tag

Product Gene Name

FURIN recombinant protein

Product Synonym Names

FUR; PACE; PCSK3; SPC1

Host

HEK293

Form/Format

Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Purity/Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Preparation and Storage

Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Molecular Weight

86,678 Da

OMIM

136950

3D Structure

ModBase 3D Structure for P09958

Tag

C-6×His tag

Product Categories/Family for FURIN recombinant protein

Bioactive Protein

Other Notes

Small volumes of FURIN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FURIN purchase

MBS189167 is a recombinant protein targeting FURIN. Also known as Human FURIN Protein, His Tag. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for FURIN. It may not necessarily be applicable to this product.

NCBI GI #

577019578

NCBI GeneID

5045

NCBI Accession #

NP_001276752.1

UniProt Primary Accession #

P09958

UniProt Secondary Accession #

Q14336; Q6LBS3; Q9UCZ5

UniProt Related Accession #

P09958

GenBank Nucleotide #

NM_001289823.1

NCBI Official Full Name

furin preproprotein

NCBI Official Synonym Full Names

furin, paired basic amino acid cleaving enzyme

NCBI Official Symbol

FURIN

NCBI Official Synonym Symbols

FUR; PACE; SPC1; PCSK3

UniProt Protein Name

Furin

UniProt Synonym Protein Names

Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACE

Protein Family

Furin

UniProt Gene Name

FURIN

UniProt Synonym Gene Names

FUR; PACE; PCSK3; PACE

UniProt Entry Name

FURIN_HUMAN

NCBI Protein Information

furin

UniProt Comments for FURIN

FURIN: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Belongs to the peptidase S8 family. Furin subfamily.

Protein type: Cell surface; EC 3.4.21.75; Membrane protein, integral; Protease; Vesicle

Chromosomal Location of Human Ortholog: 15q26.1

Cellular Component: cell surface; endoplasmic reticulum; extracellular space; Golgi lumen; Golgi membrane; lipid raft; membrane; plasma membrane; trans-Golgi network; trans-Golgi network transport vesicle

Molecular Function: endopeptidase activity; nerve growth factor binding; peptidase activity; peptide binding; protease binding; protein binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity

Biological Process: cell proliferation; cellular protein metabolic process; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; negative regulation of low-density lipoprotein receptor catabolic process; negative regulation of nerve growth factor production; negative regulation of transforming growth factor-beta1 production; nerve growth factor processing; nerve growth factor production; peptide biosynthetic process; peptide hormone processing; positive regulation of membrane protein ectodomain proteolysis; protein processing; regulation of endopeptidase activity; regulation of protein catabolic process; secretion by cell; signal peptide processing; transforming growth factor beta receptor signaling pathway; viral infectious cycle; viral protein processing

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FURIN recombinant protein

Reference Product	PubMed Publications
NOTCH1 recombinant protein	>20 publications with FURIN and NOTCH1
MMP14 recombinant protein	>14 publications with FURIN and MMP14
THBS1 recombinant protein	>13 publications with FURIN and THBS1
TGOLN2 recombinant protein	>11 publications with FURIN and TGOLN2
TIMP2 recombinant protein	>2 publications with FURIN and TIMP2
COL23A1 recombinant protein	>1 publications with FURIN and COL23A1

Pathways associated with FURIN recombinant protein

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Amyloid Fiber Formation Pathway antibodies	Amyloid Fiber Formation Pathway Diagram
Assembly Of The HIV Virion Pathway antibodies	Assembly Of The HIV Virion Pathway Diagram
Collagen Degradation Pathway antibodies	Collagen Degradation Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Delta-Notch Signaling Pathway antibodies	Delta-Notch Signaling Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Elastic Fibre Formation Pathway antibodies	Elastic Fibre Formation Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram

Diseases associated with FURIN recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>93 publications with FURIN and Necrosis
Carcinoma Antibodies	>92 publications with FURIN and Carcinoma
Nervous System Diseases Antibodies	>88 publications with FURIN and Nervous System Diseases
Immune System Diseases Antibodies	>70 publications with FURIN and Immune System Diseases
Cardiovascular Diseases Antibodies	>69 publications with FURIN and Cardiovascular Diseases
Inflammation Antibodies	>57 publications with FURIN and Inflammation
Lung Diseases Antibodies	>34 publications with FURIN and Lung Diseases
Kidney Diseases Antibodies	>32 publications with FURIN and Kidney Diseases
Heart Diseases Antibodies	>31 publications with FURIN and Heart Diseases
Adenocarcinoma Antibodies	>28 publications with FURIN and Adenocarcinoma

Organs/Tissues associated with FURIN recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>291 publications with FURIN and Blood
Brain Antibodies	>218 publications with FURIN and Brain
Liver Antibodies	>136 publications with FURIN and Liver
Kidney Antibodies	>136 publications with FURIN and Kidney
Bone Antibodies	>109 publications with FURIN and Bone
Vascular Antibodies	>95 publications with FURIN and Vascular
Nerve Antibodies	>95 publications with FURIN and Nerve
Lung Antibodies	>88 publications with FURIN and Lung
Ovary Antibodies	>79 publications with FURIN and Ovary
Heart Antibodies	>57 publications with FURIN and Heart