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Anionic Trypsin-1 (TRY1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9422454

MBS9422454 is a recombinant protein targeting TRY1. Also known as Recombinant Rattus norvegicus Anionic trypsin-1. Reactive in Rat. Host: Yeast. More details

$355 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Anionic trypsin-1 (TRY1), Recombinant Protein
Full Product Name
Recombinant Rattus norvegicus Anionic trypsin-1
Product Gene Name
TRY1 recombinant protein
Product Synonym Names
Anionic trypsin IPretrypsinogen ISerine protease 1
Host
Yeast
Species Reactivity
Rat
Form/Format
20mM Tris-HCl based buffer, pH8.0
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Molecular Weight
25.6kD
Sequence Positions
Full Length, 24
3D Structure
ModBase 3D Structure for P00762
Tag Info
His-tag

Other Notes

Small volumes of TRY1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRY1. It may not necessarily be applicable to this product.

NCBI GI #
6981420
NCBI GeneID
24691
NCBI Accession #
NP_036767.1
UniProt Primary Accession #
P00762
UniProt Related Accession #
P00762
GenBank Nucleotide #
NM_012635.1
NCBI Official Full Name
anionic trypsin-1
NCBI Official Synonym Full Names
protease, serine 1
NCBI Official Symbol
Prss1
NCBI Official Synonym Symbols
Try1; PTRYI; RATPTRYI
UniProt Protein Name
Anionic trypsin-1
UniProt Synonym Protein Names
Anionic trypsin I; Pretrypsinogen I; Serine protease 1
Protein Family
Anionic trypsin
UniProt Gene Name
Prss1
UniProt Synonym Gene Names
Try1
NCBI Protein Information
anionic trypsin-1

NCBI Summary for TRY1

catalyzes the cleavage of Arg-Xaa, Lys-Xaa [RGD, Feb 2006]

UniProt Comments for TRY1

trypsin 1: Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.4; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q23

Cellular Component: extracellular region; extracellular space

Molecular Function: calcium ion binding; serine-type endopeptidase activity

Biological Process: collagen catabolic process; digestion; proteolysis; response to caffeine; response to nicotine; response to nutrient; response to organic substance
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Research Articles on TRY1

1. These results indicate that mucin plays an important role in the preservation of the mucosal barrier and that ischemia but not digestive enzymes disturbs mucin integrity, while digestive enzymes actively mediate epithelial cell disruption.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TRY1 recombinant protein

 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Alpha-defensins Pathway antibodies  Alpha-defensins Pathway Diagram
 Antimicrobial Peptides Pathway antibodies  Antimicrobial Peptides Pathway Diagram
 Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway antibodies  Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram

Diseases associated with TRY1 recombinant protein

 Disease Name  Pubmed Publications
 Pancreatitis Antibodies  >266 publications with TRY1 and Pancreatitis
 Pancreatitis, Chronic Antibodies  >211 publications with TRY1 and Pancreatitis, Chronic
 Hereditary pancreatitis Antibodies  >113 publications with TRY1 and Hereditary pancreatitis
 Fibrosis Antibodies  >108 publications with TRY1 and Fibrosis
 Inflammation Antibodies  >27 publications with TRY1 and Inflammation
 Carcinoma Antibodies  >21 publications with TRY1 and Carcinoma
 Immune System Diseases Antibodies  >14 publications with TRY1 and Immune System Diseases
 Breast Neoplasms Antibodies  >6 publications with TRY1 and Breast Neoplasms
 Necrosis Antibodies  >6 publications with TRY1 and Necrosis
 Liver Diseases Antibodies  >5 publications with TRY1 and Liver Diseases

Organs/Tissues associated with TRY1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >105 publications with TRY1 and Pancreas
 Liver Antibodies  >13 publications with TRY1 and Liver
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