EIF3K Antibody (C-Term) Blocking Peptide

Name: EIF3K Antibody (C-Term) Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS9222003
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9222003

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A,… More details

$455 / 0.5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EIF3K, Blocking Peptide

Full Product Name

EIF3K Antibody (C-term) Blocking Peptide

Product Gene Name

EIF3K blocking peptide

Product Synonym Names

Eukaryotic translation initiation factor 3 subunit K ; eIF3k ; Eukaryotic translation initiation factor 3 subunit 12 ; Muscle-specific gene M9 protein; PLAC-24; eIF-3 p25 ; eIF-3 p28; EIF3K

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

EIF3K peptide (MBS9222003) is used for blocking the activity of EIF3K antibody (MBS9213303)

Molecular Weight

24,484 Da

OMIM

609596

Cellular Location

Nucleus. Cytoplasm

Tissue Location

Ubiquitous, with the highest levels of expression in brain, testis and kidney

Other Notes

Small volumes of EIF3K blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EIF3K purchase

MBS9222003 is a blocking peptide targeting EIF3K. Also known as EIF3K Antibody (C-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF3K. It may not necessarily be applicable to this product.

NCBI GI #

23396628

NCBI GeneID

27335

NCBI Accession #

Q9UBQ5.1

UniProt Primary Accession #

Q9UBQ5

UniProt Secondary Accession #

Q96IQ0; Q9Y6D1; A8K0I9; B7ZAM9

UniProt Related Accession #

Q9UBQ5

NCBI Official Full Name

Eukaryotic translation initiation factor 3 subunit K

NCBI Official Synonym Full Names

eukaryotic translation initiation factor 3 subunit K

NCBI Official Symbol

EIF3K

NCBI Official Synonym Symbols

M9; ARG134; PLAC24; PTD001; EIF3S12; HSPC029; MSTP001; PLAC-24; PRO1474; EIF3-p28

UniProt Protein Name

Eukaryotic translation initiation factor 3 subunit K

UniProt Synonym Protein Names

Eukaryotic translation initiation factor 3 subunit 12

Protein Family

Eukaryotic translation initiation factor

UniProt Gene Name

EIF3K

UniProt Synonym Gene Names

eIF3k

UniProt Entry Name

EIF3K_HUMAN

NCBI Protein Information

eukaryotic translation initiation factor 3 subunit K

NCBI Summary for EIF3K

The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]

UniProt Comments for EIF3K

EIF3K: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit K family.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: cytoplasm; cytosol; eukaryotic translation initiation factor 3 complex; membrane

Molecular Function: protein binding; translation initiation factor activity

Biological Process: translational initiation

Research Articles on EIF3K

1. eIF3K subunit interacts directly with the PML protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EIF3K blocking peptide

Reference Product	PubMed Publications
EIF3E blocking peptide	>11 publications with EIF3K and EIF3E
EIF3C blocking peptide	>3 publications with EIF3K and EIF3C
EIF3L blocking peptide	>3 publications with EIF3K and EIF3L
EIF3J blocking peptide	>2 publications with EIF3K and EIF3J
EIF3H blocking peptide	>2 publications with EIF3K and EIF3H
EIF3G blocking peptide	>2 publications with EIF3K and EIF3G
EIF3D blocking peptide	>1 publications with EIF3K and EIF3D
EIF3M blocking peptide	>1 publications with EIF3K and EIF3M
EIF3I blocking peptide	>1 publications with EIF3K and EIF3I
EIF3F blocking peptide	>1 publications with EIF3K and EIF3F

Pathways associated with EIF3K blocking peptide

Products by Pathway	Pathway Diagram
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies	Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
Cap-dependent Translation Initiation Pathway antibodies	Cap-dependent Translation Initiation Pathway Diagram
Eukaryotic Translation Initiation Pathway antibodies	Eukaryotic Translation Initiation Pathway Diagram
Formation Of A Pool Of Free 40S Subunits Pathway antibodies	Formation Of A Pool Of Free 40S Subunits Pathway Diagram
Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies	Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies	GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway antibodies	L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Ribosomal Scanning And Start Codon Recognition Pathway antibodies	Ribosomal Scanning And Start Codon Recognition Pathway Diagram

Organs/Tissues associated with EIF3K blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with EIF3K and Brain
Liver Antibodies	>3 publications with EIF3K and Liver
Adipose Tissue Antibodies	>2 publications with EIF3K and Adipose Tissue
Muscle Antibodies	>2 publications with EIF3K and Muscle
Blood Antibodies	>2 publications with EIF3K and Blood
Mammary Gland Antibodies	>2 publications with EIF3K and Mammary Gland
Connective Tissue Antibodies	>1 publications with EIF3K and Connective Tissue